This grant is for the purpose of accelerating research to enhance the understanding and treatment of Guillain Barre Syndrome (GBS) and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). Eligible applications should propose studies focusing on immunological mechanisms causing nerve damage, genetic and epigenetic contributions, and the development of new animal or cellular model systems. Furthermore, research may involve the discovery of novel diagnostic or treatment response biomarkers, and the investigation of new treatments or the mechanisms of action for existing therapies. The initiative aims to significantly advance medical knowledge and therapeutic options for these complex neurological conditions.
Opportunity ID: 357090
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-NS-25-025 |
| Funding Opportunity Title: | Exploratory/Developmental Research on Guillain Barre Syndrome (GBS) and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (R21 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 13, 2024 |
| Last Updated Date: | Nov 13, 2024 |
| Original Closing Date for Applications: | Oct 03, 2025 |
| Current Closing Date for Applications: | Oct 03, 2025 |
| Archive Date: | Nov 08, 2025 |
| Estimated Total Program Funding: | $3,000,000 |
| Award Ceiling: | $3,000,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses County governments Independent school districts City or township governments Special district governments Public housing authorities/Indian housing authorities Small businesses Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this initiative are to accelerate research leading to improved understanding and treatments for Guillain Barre Syndrome (GBS) and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). Responsive applications would propose studies of immunological mechanisms of nerve damage/dysfunction, contributing genetic/epigenetic factors, novel animal/cellular model systems, discovery of novel diagnostic or treatment response biomarkers, novel treatments or mechanisms of action of existing treatments. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-025.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357090 Full Announcement-RFA-NS-25-025 -> RFA-NS-25-025-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288700 | Feb 03, 2025 | Oct 03, 2025 | View |
Package 1
Mandatory forms
357090 RR_SF424_5_0-5.0.pdf
357090 PHS398_CoverPageSupplement_5_0-5.0.pdf
357090 RR_OtherProjectInfo_1_4-1.4.pdf
357090 PerformanceSite_4_0-4.0.pdf
357090 RR_KeyPersonExpanded_4_0-4.0.pdf
357090 PHS398_ResearchPlan_5_0-5.0.pdf
357090 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357090 RR_Budget_3_0-3.0.pdf
357090 RR_SubawardBudget30_3_0-3.0.pdf
357090 PHS398_ModularBudget_1_2-1.2.pdf
357090 PHS_AssignmentRequestForm_4_0-4.0.pdf
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