This grant from the National Institutes of Health is for the purpose of funding innovative R01 studies exploring the intricate relationship between environmental toxicant exposures and epitranscriptomic crosstalks. Successful applications will propose research to understand how toxicants may inhibit, create new, or otherwise alter these critical interactions. The initiative specifically seeks mechanistic insights into how such altered epitranscriptomic crosstalks contribute to the initiation, progression, and/or exacerbation of adverse health outcomes. Epitranscriptomic crosstalks are broadly defined as the interactions between epitranscriptomic marks and their associated Readers, Writers, Erasers (RWEs), epigenomic marks, and genomic structures.
Opportunity ID: 357119
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-ES-25-001 |
| Funding Opportunity Title: | Epitranscriptomics Crosstalks and Toxicants (EPCOT) (R01 Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Environment Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 14, 2024 |
| Last Updated Date: | Nov 14, 2024 |
| Original Closing Date for Applications: | Feb 06, 2025 |
| Current Closing Date for Applications: | Feb 06, 2025 |
| Archive Date: | Mar 14, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) Small businesses City or township governments Public and State controlled institutions of higher education County governments Public housing authorities/Indian housing authorities State governments Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this initiative is to solicit new R01 applications that propose innovative studies to explore how exposures to environmental toxicants may inhibit, create new or otherwise impact epitranscriptomic crosstalks and provide mechanistic insights into how these interactions play a role in initiation, progression, and/or exacerbation of adverse health outcomes. Epitranscriptomic crosstalks are defined as interactions between epitranscriptomic marks and associated Readers Writers and Erasers (RWEs) and epigenomic marks and/or epigenomic RWEs, and genomic structures. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-ES-25-001.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357119 Full Announcement-RFA-ES-25-001 -> RFA-ES-25-001-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288721 | Jan 06, 2025 | Feb 06, 2025 | View |
Package 1
Mandatory forms
357119 RR_SF424_5_0-5.0.pdf
357119 PHS398_CoverPageSupplement_5_0-5.0.pdf
357119 RR_OtherProjectInfo_1_4-1.4.pdf
357119 PerformanceSite_4_0-4.0.pdf
357119 RR_KeyPersonExpanded_4_0-4.0.pdf
357119 PHS398_ResearchPlan_5_0-5.0.pdf
357119 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357119 RR_Budget_3_0-3.0.pdf
357119 RR_SubawardBudget30_3_0-3.0.pdf
357119 PHS398_ModularBudget_1_2-1.2.pdf
357119 PHS_AssignmentRequestForm_4_0-4.0.pdf
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