This BRAIN Initiative grant focuses on developing and validating novel tools for in-depth analysis of complex brain circuits and cellular interactions. The grant’s purpose is to fund innovative neurotechnologies that inform or exploit cell-type and circuit-level specificity. Proposed tools may include new genetic and non-genetic methods for delivering agents to specific cells with enhanced precision and sensitivity. A strong validation plan is essential. Priority is given to approaches that break technical barriers and tools usable across multiple species, substantially improving current research capabilities into brain function.
Opportunity ID: 357137
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-MH-26-170 |
| Funding Opportunity Title: | BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.173 — Research Related to Deafness and Communication Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 15, 2024 |
| Last Updated Date: | Nov 15, 2024 |
| Original Closing Date for Applications: | Feb 08, 2027 |
| Current Closing Date for Applications: | Feb 08, 2027 |
| Archive Date: | Mar 16, 2027 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses Small businesses County governments Special district governments Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful application. The development of new genetic and non-genetic tools for delivering genes, proteins and chemicals to cells of interest or approaches that are expected to target specific cell types and/or circuits in the nervous system with greater precision and sensitivity than currently established methods are encouraged. Tools that can be used in a number of species/model organisms rather than those restricted to a single species are highly desired. Applications that provide approaches that break through existing technical barriers to substantially improve current capabilities are highly encouraged. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-26-170.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357137 Full Announcement-RFA-MH-26-170 -> RFA-MH-26-170-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288732 | Jan 07, 2025 | Feb 08, 2027 | View |
Package 1
Mandatory forms
357137 RR_SF424_5_0-5.0.pdf
357137 PHS398_CoverPageSupplement_5_0-5.0.pdf
357137 RR_OtherProjectInfo_1_4-1.4.pdf
357137 PerformanceSite_4_0-4.0.pdf
357137 RR_KeyPersonExpanded_4_0-4.0.pdf
357137 PHS398_ResearchPlan_5_0-5.0.pdf
357137 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357137 RR_Budget_3_0-3.0.pdf
357137 RR_SubawardBudget30_3_0-3.0.pdf
357137 PHS398_ModularBudget_1_2-1.2.pdf
357137 PHS_AssignmentRequestForm_4_0-4.0.pdf
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