This grant, offered by the STRIPE program, is for preclinical research investigating how radiopharmaceutical therapy (RPT) agents dynamically impact cancer biology. Supported projects will utilize state-of-the-art methods to study RPT’s effects on normal tissue, tumor cells, and the tumor microenvironment. The grant seeks hypotheses-driven studies that will provide a strong preclinical basis for developing novel RPT targeting strategies and approaches. Ultimately, insights gained will inform the rationale and design of new RPT-based clinical trials. The application deadline is May 07, 2025.
Opportunity ID: 357190
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-25-173 |
| Funding Opportunity Title: | Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE) (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.394 — Cancer Detection and Diagnosis Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 18, 2024 |
| Last Updated Date: | Nov 18, 2024 |
| Original Closing Date for Applications: | May 07, 2025 |
| Current Closing Date for Applications: | May 07, 2025 |
| Archive Date: | Jun 12, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities Special district governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Public and State controlled institutions of higher education For profit organizations other than small businesses Independent school districts City or township governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The STRIPE program seeks to support pre-clinical research projects utilizing state-of-the-art cancer biology methods and model systems that study how radiopharmaceutical therapy (RPT) agents affect the biology of normal tissue, tumor cells and the tumor microenvironment. Ideally, proposed aims will be designed to test hypotheses on how RPT dynamically impacts cancer biology processes, which can serve as the pre-clinical basis for developing new targeting strategies and approaches. Studies supported by this PAR will ultimately inform the rationale and design of new RPT-based clinical trials. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PA-25-173.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357190 Full Announcement-PA-25-173 -> PA-25-173-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288778 | Jan 16, 2025 | May 07, 2025 | View |
Package 1
Mandatory forms
357190 RR_SF424_5_0-5.0.pdf
357190 PHS398_CoverPageSupplement_5_0-5.0.pdf
357190 RR_OtherProjectInfo_1_4-1.4.pdf
357190 PerformanceSite_4_0-4.0.pdf
357190 RR_KeyPersonExpanded_4_0-4.0.pdf
357190 PHS398_ResearchPlan_5_0-5.0.pdf
357190 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357190 RR_Budget_3_0-3.0.pdf
357190 RR_SubawardBudget30_3_0-3.0.pdf
357190 PHS398_ModularBudget_1_2-1.2.pdf
357190 PHS_AssignmentRequestForm_4_0-4.0.pdf
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