This grant is for funding research projects that investigate the critical link between social disconnection, encompassing both objective social isolation and perceived loneliness, and suicide risk among older adults. The primary purpose is to identify underlying neurobiological and environmental mechanisms that contribute to increased suicidal thoughts and behaviors in late life due to social disconnection. Furthermore, it seeks to support projects utilizing experimental therapeutic approaches to pinpoint intervention targets and develop and test strategies for preventing late-life suicide. The initiative also encourages the development and modification of service delivery models aimed at enhancing social connection in older adults, thereby reducing suicide risk and improving overall well-being.
Opportunity ID: 357198
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-066 |
| Funding Opportunity Title: | Social disconnection and Suicide Risk in Late Life (R21 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 18, 2024 |
| Last Updated Date: | Nov 18, 2024 |
| Original Closing Date for Applications: | Sep 07, 2026 |
| Current Closing Date for Applications: | Sep 07, 2026 |
| Archive Date: | Oct 13, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses County governments Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Independent school districts Private institutions of higher education City or township governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Special district governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This initiative seeks to solicit applications for research projects that address the link between social disconnection including both objective social isolation as well as perceived social isolation (otherwise known as loneliness) and suicide in late-life. Emphasis is placed on research that identifies neurobiological and environmental mechanisms associated with social isolation and loneliness that increase risk for suicidal thoughts and behavior in late-life, that uses an experimental therapeutics approach to identify targets and develop and test interventions to prevent late-life suicide, and that develops new and modifies existing service delivery models to enhance social connection in late-life to prevent suicide. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-066.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357198 Full Announcement-PAR-25-066 -> PAR-25-066-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288786 | Jan 16, 2025 | Sep 07, 2026 | View |
Package 1
Mandatory forms
357198 RR_SF424_5_0-5.0.pdf
357198 PHS398_CoverPageSupplement_5_0-5.0.pdf
357198 RR_OtherProjectInfo_1_4-1.4.pdf
357198 PerformanceSite_4_0-4.0.pdf
357198 RR_KeyPersonExpanded_4_0-4.0.pdf
357198 PHS398_ResearchPlan_5_0-5.0.pdf
357198 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357198 RR_Budget_3_0-3.0.pdf
357198 RR_SubawardBudget30_3_0-3.0.pdf
357198 PHS398_ModularBudget_1_2-1.2.pdf
357198 PHS_AssignmentRequestForm_4_0-4.0.pdf
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