This NIDA Avant-Garde Grant is for exceptional scientists proposing high-impact research to open new areas in HIV/AIDS, specifically addressing issues relevant to drug abuse, or leading to novel prevention and treatment avenues for drug abusers. Described as ‘avant-garde,’ the program seeks highly innovative and potentially transformative approaches. Proposed research must significantly differ from existing work by the investigator or others, aligning with NIH HIV/AIDS Research Priorities. The grant aims to support creative basic research that can lead to improved preventive interventions or therapies, new strategies to prevent disease transmission, better disease outcomes, or ultimately, the eradication of HIV or enhanced lives for those living with the virus, fostering groundbreaking advancements in the field.
Opportunity ID: 357292
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-261 |
| Funding Opportunity Title: | NIDA Avant-Garde Program for HIV and Substance Use Disorder Research (DP1 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Use and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 21, 2024 |
| Last Updated Date: | Nov 21, 2024 |
| Original Closing Date for Applications: | Aug 15, 2025 |
| Current Closing Date for Applications: | Aug 15, 2025 |
| Archive Date: | Sep 20, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $700,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) Special district governments Private institutions of higher education Small businesses Native American tribal organizations (other than Federally recognized tribal governments) County governments State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NIDA Avant-Garde Award Program for HIV/AIDS Research supports individual scientists of exceptional creativity who propose high-impact research that will open new areas of HIV/AIDS research relevant to drug abuse and/or lead to new avenues for prevention and treatment of HIV/AIDS among drug abusers. The term avant-garde is used to describe highly innovative approaches that have the potential to be transformative. The proposed research should reflect approaches and ideas that are substantially different from those already being pursued by the investigator or others and should support the NIH HIV/AIDS Research Priorities https://grants.nih.gov/grants/guide/notice-files/NOT-OD-20-018.html. The NIDA Avant-Garde award supports innovative, basic research that may lead to improved preventive interventions or therapies; creative, new strategies to prevent disease transmission; novel approaches to improve disease outcomes; and creative approaches to eradicating HIV or improving the lives of those living with HIV. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-261.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357292 Full Announcement-PAR-25-261 -> PAR-25-261-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288871 | Jul 15, 2025 | Aug 15, 2025 | View |
Package 1
Mandatory forms
357292 RR_SF424_5_0-5.0.pdf
357292 PerformanceSite_4_0-4.0.pdf
357292 RR_OtherProjectInfo_1_4-1.4.pdf
357292 RR_KeyPersonExpanded_4_0-4.0.pdf
357292 PHS398_CoverPageSupplement_5_0-5.0.pdf
357292 PHS398_ResearchPlan_5_0-5.0.pdf
357292 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357292 PHS_AssignmentRequestForm_4_0-4.0.pdf
357292 RR_Budget10_3_0-3.0.pdf
357292 RR_SubawardBudget10_30_3_0-3.0.pdf
357292 PHS398_ModularBudget_1_2-1.2.pdf
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