The NHLBI Catalyze Program offers this grant to accelerate the transition of basic science discoveries into viable diagnostic and therapeutic candidates, preparing them for human testing. This initiative also aims to cultivate translational researchers skilled in product development and entrepreneurship. Specifically, this Catalyze Product Definition grant is for providing essential early-stage translational support. Its purpose is to facilitate the identification and characterization of potential therapeutic candidates, including small molecules, biologics, and combination products, to effectively treat Heart, Lung, Blood, and Sleep (HLBS) diseases and disorders. It is part of a larger suite of innovation grants designed to advance projects to meet entry criteria for the NHLBI Catalyze Preclinical Program.
Opportunity ID: 357337
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-26-018 |
| Funding Opportunity Title: | Catalyze: Product Definition for Small Molecules, Biologics, and Combination Products – Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 22, 2024 |
| Last Updated Date: | Nov 22, 2024 |
| Original Closing Date for Applications: | Dec 23, 2027 |
| Current Closing Date for Applications: | Dec 23, 2027 |
| Archive Date: | Jan 28, 2028 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments For profit organizations other than small businesses Small businesses Independent school districts Private institutions of higher education Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of basic science discoveries into viable diagnostic and therapeutic candidates that have been cleared for human testing, and to develop translational researchers fluent in product development and entrepreneurship. This specific Catalyze Product Definition initiative will provide the early stage translational support needed for the activities required to identify and characterize potential therapeutic candidates and combination products to treat HLBS diseases and disorders. This initiative has a companion initiative that supports development of devices and diagnostics and is also part of a suite of innovation grants to advance projects to the point where they can meet the entry criteria for the NHLBI Catalyze Preclinical Program. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-018.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357337 Full Announcement-RFA-HL-26-018 -> RFA-HL-26-018-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288954 | Jan 11, 2025 | Dec 23, 2027 | View |
Package 1
Mandatory forms
357337 RR_SF424_5_0-5.0.pdf
357337 PHS398_CoverPageSupplement_5_0-5.0.pdf
357337 RR_OtherProjectInfo_1_4-1.4.pdf
357337 PerformanceSite_4_0-4.0.pdf
357337 RR_KeyPersonExpanded_4_0-4.0.pdf
357337 RR_Budget_3_0-3.0.pdf
357337 PHS398_ResearchPlan_5_0-5.0.pdf
357337 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357337 RR_SubawardBudget30_3_0-3.0.pdf
357337 PHS_AssignmentRequestForm_4_0-4.0.pdf
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