This grant is for the purpose of advancing pain management research by developing and rigorously validating non-rodent mammalian models of pain. These models, along with associated outcome measures and endpoints, are crucial for enabling effective translational research. The initiative seeks models that accurately reflect the molecular, cellular, pathological, behavioral, and cognitive complexities of human pain conditions. The ultimate goal is to generate well-validated models and measures that facilitate the discovery and development of non-opioid analgesic therapies. This research aims to provide safer, more effective treatments for pain with significantly reduced addiction potential, addressing a critical public health need.
Opportunity ID: 343016
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-NS-22-070 |
| Funding Opportunity Title: | HEAL Initiative: Development and Validation of Non-Rodent Mammalian Models of Pain(R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Food and Nutrition Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 09, 2022 |
| Last Updated Date: | Aug 09, 2022 |
| Original Closing Date for Applications: | Mar 06, 2024 |
| Current Closing Date for Applications: | Mar 06, 2024 |
| Archive Date: | Apr 11, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $750,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Small businesses Private institutions of higher education Native American tribal governments (Federally recognized) County governments For profit organizations other than small businesses Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Public and State controlled institutions of higher education State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This funding opportunity announcement (FOA) invites research to develop, characterize, and rigorously validate non-rodent mammalian models of pain, associated outcome measures and/or endpoints that enable translational research for effective pain management. These models are expected to recapitulate molecular, cellular, pathological, behavioral, and/or cognitive aspects of human pain disorders and conditions. Research supported under this FOA is expected to provide well-validated models and measures that facilitate the development of non-opioid analgesic therapeutic interventions with little or no addiction liability. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-22-070.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 343016 Full Announcement-RFA-NS-22-070 -> RFA-NS-22-070-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00276322 | Oct 04, 2022 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00277896 | Nov 01, 2022 | Mar 06, 2024 | View |
Package 1
Mandatory forms
343016 RR_SF424_5_0-5.0.pdf
343016 PHS398_CoverPageSupplement_5_0-5.0.pdf
343016 RR_OtherProjectInfo_1_4-1.4.pdf
343016 PerformanceSite_4_0-4.0.pdf
343016 RR_KeyPersonExpanded_4_0-4.0.pdf
343016 PHS398_ResearchPlan_4_0-4.0.pdf
343016 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343016 RR_Budget_3_0-3.0.pdf
343016 RR_SubawardBudget30_3_0-3.0.pdf
343016 PHS398_ModularBudget_1_2-1.2.pdf
343016 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
343016 RR_SF424_5_0-5.0.pdf
343016 PHS398_CoverPageSupplement_5_0-5.0.pdf
343016 RR_OtherProjectInfo_1_4-1.4.pdf
343016 PerformanceSite_4_0-4.0.pdf
343016 RR_KeyPersonExpanded_4_0-4.0.pdf
343016 PHS398_ResearchPlan_5_0-5.0.pdf
343016 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343016 RR_Budget_3_0-3.0.pdf
343016 RR_SubawardBudget30_3_0-3.0.pdf
343016 PHS398_ModularBudget_1_2-1.2.pdf
343016 PHS_AssignmentRequestForm_3_0-3.0.pdf
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