This National Institutes of Health (NIH) R01 grant is for basic research exploring how the microenvironment influences lung progenitor cell function. It aims to elucidate the impact of cellular components, extracellular matrix, and soluble factors on lung progenitor cells during development, homeostasis, repair, and regeneration. The grant encourages innovative, hypothesis-based studies from multi-disciplinary teams to advance lung stem cell biology, a critical and understudied area. Furthermore, this funding opportunity will support the development of novel 3-dimensional, multi-component models to interrogate lung stem cell niches, fostering new insights into these vital cellular environments.
Opportunity ID: 294658
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-18-022 |
| Funding Opportunity Title: | The Impact of Microenvironment on Lung Progenitor Cell Function (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 4 |
| Assistance Listings: | 93.838 — Lung Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 14, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 16, 2018 |
| Current Closing Date for Applications: | Jan 16, 2018 |
| Archive Date: | Feb 21, 2018 |
| Estimated Total Program Funding: | $2,172,000 |
| Award Ceiling: | $350,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Independent school districts Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Public and State controlled institutions of higher education Private institutions of higher education Small businesses City or township governments For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites applications for basic research to elucidate the impact of microenvironment, which includes cellular components of the niche, extracellular matrix, and soluble factors, on lung progenitor cell phenotype and function during development, homeostasis, repair and regeneration. Multi-disciplinary teams with complementary expertise are encouraged to propose innovative, hypothesis-based studies to catalyze this understudied area critical to advancing lung stem cell biology. This FOA will also support the development of novel 3-dimensional, multi-component models to interrogate lung stem cell niches. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-18-022.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00233210 | Sep 04, 2017 | Jan 16, 2018 | View |
Package 1
Mandatory forms
294658 RR_SF424_2_0-2.0.pdf
294658 PHS398_CoverPageSupplement_3_0-3.0.pdf
294658 RR_OtherProjectInfo_1_3-1.3.pdf
294658 PerformanceSite_2_0-2.0.pdf
294658 RR_KeyPersonExpanded_2_0-2.0.pdf
294658 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
294658 RR_Budget_1_3-1.3.pdf
294658 RR_SubawardBudget30_1_3-1.3.pdf
294658 PHS398_ModularBudget_1_2-1.2.pdf
294658 PHS_Inclusion_Enrollment_Report-1.0.pdf
294658 PHS_AssignmentRequestForm-1.0.pdf