This NHLBI small grant program (R03) is for current or recently completed NHLBI K01, K08, K23, and K25 awardees. Its core purpose is to offer essential support to expand existing research objectives or embark on new studies directly resulting from their K award. This initiative aims to significantly enhance the awardees’ capabilities as they transition to fully independent investigator status within the scientific community. The R03 mechanism is designed for short-term projects, typically two years or less, requiring limited resources. These studies are intended to generate crucial preliminary data to bolster future R01-equivalent applications. Eligible projects encompass pilot studies, proof-of-concept, secondary data analysis, or developing novel research methodologies. A minimum of 40% protected research effort is required.
Opportunity ID: 357741
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-25-011 |
| Funding Opportunity Title: | Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 16, 2024 |
| Last Updated Date: | Dec 16, 2024 |
| Original Closing Date for Applications: | Jan 07, 2026 |
| Current Closing Date for Applications: | Jan 07, 2026 |
| Archive Date: | Feb 12, 2026 |
| Estimated Total Program Funding: | $75,000 |
| Award Ceiling: | $75,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments Independent school districts For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) City or township governments Public housing authorities/Indian housing authorities County governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to solicit current or recently completed NHLBI K01, K08, K23, and K25 awardees for small grant support to expand their current research objectives or to branch out to a new study that resulted from the research conducted under the K award. Active NHLBI K01, K08, K23, and K25 awardees may apply for R03 support after the notices of award (NoA) for their first type-5 K awards have been issued. Recently completed NHLBI K01, K08, K23, and K25 awardees are eligible to apply for the R03 if the earliest possible R03 start date falls within 2 years of their prior NHLBI K award Project Period end date. This FOA is intended to enhance the capability of NHLBI K01, K08, K23, and K25 awardees to conduct research as they complete their transition to fully independent investigator status. This R03 grant mechanism is intended to support research projects that can be carried out and completed within a short period of time (no more than two years) with limited resources and that may generate preliminary data to support a subsequent R01-equivalent application. These studies include, but not limited to, pilot or feasibility studies; proof of concept studies; secondary analysis of existing data; small, self-contained research projects; development of new research methodologies or technologies, or development of novel experimental models. For current and previous K23 awardees, research proposed in the R03 application may or may not include patient-oriented research. A minimum of 40% protected overall research effort is required from applicants during the R03 award period and can be met through a combination of effort on the proposed R03 and other research projects, regardless of funding source. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-25-011.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357741 Full Announcement-RFA-HL-25-011 -> RFA-HL-25-011-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289683 | Jan 13, 2025 | Jan 07, 2026 | View |
Package 1
Mandatory forms
357741 RR_SF424_5_0-5.0.pdf
357741 PHS398_CoverPageSupplement_5_0-5.0.pdf
357741 RR_OtherProjectInfo_1_4-1.4.pdf
357741 PerformanceSite_4_0-4.0.pdf
357741 RR_KeyPersonExpanded_4_0-4.0.pdf
357741 PHS398_ResearchPlan_5_0-5.0.pdf
357741 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357741 RR_Budget_3_0-3.0.pdf
357741 RR_SubawardBudget30_3_0-3.0.pdf
357741 PHS398_ModularBudget_1_2-1.2.pdf
357741 PHS_AssignmentRequestForm_4_0-4.0.pdf
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