The National Cancer Institute (NCI) is offering the Toward Translation of Nanotechnology Cancer Interventions (TTNCI) grant to support advanced pre-clinical research, specifically for nanotechnology-based cancer diagnostics and therapeutics. This grant is for maturing experimental nanomedicines, encompassing nanoparticles and nano-devices, which demonstrate strong potential to significantly improve cancer treatment effectiveness. This improvement is expected through the innovative combination of nanoparticle/nano-device structural design and/or the intelligent delivery of therapeutic/diagnostic cargo. TTNCI awards are designed to enable further development of these promising nanotechnology-based interventions, bringing them to a stage where they can seamlessly continue on a developmental path towards the NCI Experimental Therapeutics (NExT) and other vital NCI translational programs.
Opportunity ID: 357748
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-336 |
| Funding Opportunity Title: | Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.395 — Cancer Treatment Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 16, 2024 |
| Last Updated Date: | Dec 16, 2024 |
| Original Closing Date for Applications: | Nov 15, 2027 |
| Current Closing Date for Applications: | Nov 15, 2027 |
| Archive Date: | Dec 21, 2027 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Independent school districts Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education State governments City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Through this Notice of Funding Opportunity (NOFO), entitled “Toward Translation of Nanotechnology Cancer Interventions” (TTNCI), the National Cancer Institute (NCI) encourages applications for advanced pre-clinical research, supporting translation of nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards are designed to mature experimental nanomedicines relying on nanoparticles and nano-devices which demonstrate strong potential to improve cancer treatment effectiveness due to the combination of nanoparticle/nano-device structural design and/or therapeutic/diagnostic cargo which is delivered. TTNCI awards are expected to enable further development of proposed nanotechnology-based interventions to the stage in which they could continue on a developmental path towards the NCI Experimental Therapeutics (NExT) and other NCI translational programs. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-336.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357748 Full Announcement-PAR-25-336 -> PAR-25-336-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289690 | Apr 19, 2025 | Nov 15, 2027 | View |
Package 1
Mandatory forms
357748 RR_SF424_5_0-5.0.pdf
357748 PHS398_CoverPageSupplement_5_0-5.0.pdf
357748 RR_OtherProjectInfo_1_4-1.4.pdf
357748 PerformanceSite_4_0-4.0.pdf
357748 RR_KeyPersonExpanded_4_0-4.0.pdf
357748 PHS398_ResearchPlan_5_0-5.0.pdf
357748 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357748 RR_Budget_3_0-3.0.pdf
357748 RR_SubawardBudget30_3_0-3.0.pdf
357748 PHS398_ModularBudget_1_2-1.2.pdf
357748 PHS_AssignmentRequestForm_4_0-4.0.pdf
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