This grant, jointly offered by the National Institute of Allergy and Infectious Diseases (NIAID), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute on Drug Abuse (NIDA), and National Institute on Alcohol Abuse and Alcoholism (NIAAA), is specifically designed to create research opportunities for a critical demographic: new and ‘at-risk’ investigators. As an R01 mechanism, it includes an optional clinical trial component, indicating its broad applicability across various biomedical research fields relevant to the participating institutes. While a detailed description of specific research priorities is not provided, the core purpose of this initiative is to support and stabilize the careers of emerging and vulnerable researchers, ensuring the continuity of scientific innovation. This targeted funding aims to empower investigators to conduct significant studies, fostering growth within the scientific community by providing essential resources for their projects.
Opportunity ID: 357956
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-25-249 |
| Funding Opportunity Title: | NIAID, NIDDK, NIDA, and NIAAA Research Opportunities for New and "At-Risk" Investigators (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.273 — Alcohol Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Dec 31, 2024 |
| Last Updated Date: | Mar 10, 2025 |
| Original Closing Date for Applications: | Sep 07, 2025 |
| Current Closing Date for Applications: | Mar 10, 2025 |
| Archive Date: | Mar 11, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments For profit organizations other than small businesses Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Independent school districts Native American tribal governments (Federally recognized) County governments City or township governments Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
Not Available |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PA-25-249.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Closed | Mar 10, 2025 | |
| Dec 31, 2024 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-25-249 |
| Funding Opportunity Title: | NIAID, NIDDK, NIDA, and NIAAA Research Opportunities for New and "At-Risk" Investigators (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.273 — Alcohol Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Dec 31, 2024 |
| Last Updated Date: | Mar 10, 2025 |
| Original Closing Date for Applications: | Sep 07, 2025 |
| Current Closing Date for Applications: | Mar 10, 2025 |
| Archive Date: | Mar 11, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments For profit organizations other than small businesses Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Independent school districts Native American tribal governments (Federally recognized) County governments City or township governments Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
Not Available |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PA-25-249.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-25-249 |
| Funding Opportunity Title: | NIAID, NIDDK, NIDA, and NIAAA Research Opportunities for New and "At-Risk" Investigators (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.273 — Alcohol Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 31, 2024 |
| Last Updated Date: | Dec 31, 2024 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Sep 07, 2025 |
| Archive Date: | Oct 13, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Independent school districts Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Private institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses City or township governments Small businesses County governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | SRF Reissue – The purpose of this notice of funding opportunity (NOFO) is to encourage applications for research projects within the mission of either the NIAID mission or the NIDDK. This NOFO seeks to support either (a) a New Investigator (NI), an individual who has not previously competed successfully for substantial, independent funding from NIH, or (b) are an ‘At-Risk’ investigator, an individual who had prior support as a PD/PI on a substantial independent research award and unless successful in securing a substantial research grant award in the current fiscal year, will have no substantial research grant funding in the following fiscal year, from diverse backgrounds, including those from groups underrepresented in the health-related sciences. The purpose of this funding opportunity announcement is to encourage applications for research projects within the mission of either the NIAID or the NIDDK. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PA-25-249.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289852 | Jan 05, 2025 | Mar 11, 2025 | View |
Package 1
Mandatory forms
357956 RR_SF424_5_0-5.0.pdf
357956 PHS398_CoverPageSupplement_5_0-5.0.pdf
357956 RR_OtherProjectInfo_1_4-1.4.pdf
357956 PerformanceSite_4_0-4.0.pdf
357956 RR_KeyPersonExpanded_4_0-4.0.pdf
357956 PHS398_ResearchPlan_5_0-5.0.pdf
357956 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357956 RR_Budget_3_0-3.0.pdf
357956 RR_SubawardBudget30_3_0-3.0.pdf
357956 PHS398_ModularBudget_1_2-1.2.pdf
357956 PHS_AssignmentRequestForm_4_0-4.0.pdf
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