This National Cancer Institute (NCI) grant encourages revision applications from currently funded NCI R01 research projects. This opportunity aims to enable researchers to significantly expand upon their original research questions or accelerate progress within their parent study. To achieve this, applicants should propose to incorporate a new technical approach or device, specifically those developed through support from the NCI Innovative Molecular Analysis Technologies (IMAT) program. The awards are intended to incentivize independent validation and accelerate the widespread adoption of these promising, emerging technologies by appropriate research communities. Furthermore, as an integral part of the NCI IMAT program, this initiative actively promotes interdisciplinary collaboration, fostering the development of innovative tools and methods essential for advancing cancer research and accelerating scientific discovery.
Opportunity ID: 357957
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-25-005 |
| Funding Opportunity Title: | Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.394 — Cancer Detection and Diagnosis Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 31, 2024 |
| Last Updated Date: | Dec 31, 2024 |
| Original Closing Date for Applications: | Oct 03, 2025 |
| Current Closing Date for Applications: | Oct 03, 2025 |
| Archive Date: | Nov 08, 2025 |
| Estimated Total Program Funding: | $150,000 |
| Award Ceiling: | $150,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) State governments Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts For profit organizations other than small businesses Public and State controlled institutions of higher education Small businesses County governments Private institutions of higher education Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to encourage revision applications (formerly called “competing revisions”) from currently funded NCI R01 research projects. The applicants should propose to expand upon the original research question(s) or otherwise accelerate progress for the parent study by incorporating a new technical approach or device developed through support from the NCI Innovative Molecular Analysis Technologies (IMAT) program. Awards from this NOFO are meant to incentivize independent validation and accelerate the adoption of these emerging technologies by appropriate research communities. As a component of the NCI IMAT program, this NOFO aims to promote interdisciplinary collaboration in the development of innovative tools and methods that enable cancer research and accelerate scientific discovery. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-25-005.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357957 Full Announcement-RFA-CA-25-005 -> RFA-CA-25-005-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289853 | Mar 04, 2025 | Oct 03, 2025 | View |
Package 1
Mandatory forms
357957 RR_SF424_5_0-5.0.pdf
357957 PHS398_CoverPageSupplement_5_0-5.0.pdf
357957 RR_OtherProjectInfo_1_4-1.4.pdf
357957 PerformanceSite_4_0-4.0.pdf
357957 RR_KeyPersonExpanded_4_0-4.0.pdf
357957 PHS398_ResearchPlan_5_0-5.0.pdf
357957 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357957 RR_Budget_3_0-3.0.pdf
357957 RR_SubawardBudget30_3_0-3.0.pdf
357957 PHS398_ModularBudget_1_2-1.2.pdf
357957 PHS_AssignmentRequestForm_4_0-4.0.pdf
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