This grant from the National Institutes of Health is for the purpose of advancing in vivo high-resolution structural and functional imaging technologies for the living human inner ear. The program seeks proposals to significantly improve existing imaging or develop novel techniques with greater detail, including dynamic elements. Projects may also focus on creating new imaging probes or contrast agents to enhance visualization. The ultimate goal is to enable non-invasive, detailed visualization of inner ear structures like hair cells, otoliths, and vasculature in awake patients within a clinical setting. A multi-disciplinary approach is highly encouraged. Studies in humans and intermediate mammalian animal models are permitted, provided a clear path to human application is defined.
Opportunity ID: 358022
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DC-25-005 |
| Funding Opportunity Title: | In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.173 — Research Related to Deafness and Communication Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 06, 2025 |
| Last Updated Date: | Jan 06, 2025 |
| Original Closing Date for Applications: | Oct 01, 2026 |
| Current Closing Date for Applications: | Oct 01, 2026 |
| Archive Date: | Nov 06, 2026 |
| Estimated Total Program Funding: | $500,000 |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Special district governments Public housing authorities/Indian housing authorities Small businesses City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This funding opportunity aims to support the development of in vivo high-resolution structural and functional imaging technologies for the living human inner ear. Proposed projects should focus on improving the resolution of current imaging techniques or developing new imaging techniques that can visualize inner ear structures in vivo with significantly greater detail and accuracy than currently possible. Both structural and functional aspects, including visualizing dynamic elements are important to development of new and improved techniques. Projects may also focus on developing new imaging probes or contrast agents that can enhance visualization of the inner ear structures. Ultimately, research supported in response to this RFA is to encourage technologies that allow, for example, structures such as hair cells, otoliths, membranes, ions, and vasculature to be viewed in detail in awake patients in a clinical setting using non-invasive techniques. To achieve this goal, a multi-disciplinary team approach that takes advantage of the expertise of each team member is highly encouraged. Studies in humans and intermediate studies in animals, but not non-mammalian species, may be proposed to develop or advance the needed technology. Any intermediate studies must articulate a clear path of the proposed methodology to application in awake humans or define the limitations and the usefulness in anesthetized humans. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DC-25-005.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 358022 Full Announcement-RFA-DC-25-005 -> RFA-DC-25-005-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289897 | May 03, 2025 | Oct 01, 2026 | View |
Package 1
Mandatory forms
358022 RR_SF424_5_0-5.0.pdf
358022 PHS398_CoverPageSupplement_5_0-5.0.pdf
358022 RR_OtherProjectInfo_1_4-1.4.pdf
358022 PerformanceSite_4_0-4.0.pdf
358022 RR_KeyPersonExpanded_4_0-4.0.pdf
358022 PHS398_ResearchPlan_5_0-5.0.pdf
358022 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
358022 RR_Budget_3_0-3.0.pdf
358022 RR_SubawardBudget30_3_0-3.0.pdf
358022 PHS398_ModularBudget_1_2-1.2.pdf
358022 PHS_AssignmentRequestForm_4_0-4.0.pdf
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