This grant is for establishing a collaborative consortium of leading tuberculosis (TB) experts, encompassing both preclinical and clinical research domains. Its core purpose is to systematically advance and refine existing preclinical models for TB drug development. This will be achieved through rigorous analysis of extensive relevant preclinical and clinical data, ensuring that the models are highly optimized and representative. The ultimate goal is to leverage the insights derived from these enhanced models to precisely identify and validate the most promising new combination drug regimens. These identified regimens will then be prioritized and prepared for subsequent rigorous clinical testing, accelerating the discovery of more effective TB treatments. The initiative aims to streamline the development pipeline for innovative TB therapies.
Opportunity ID: 343686
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-22-059 |
| Funding Opportunity Title: | Consortium for Design of TB Drug Regimens (UM1 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 21, 2022 |
| Last Updated Date: | Sep 21, 2022 |
| Original Closing Date for Applications: | Feb 07, 2023 |
| Current Closing Date for Applications: | Feb 07, 2023 |
| Archive Date: | Mar 15, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education City or township governments Private institutions of higher education For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts County governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this FOA is to establish a consortium of tuberculosis (TB) preclinical and clinical experts to systematically refine preclinical models by analyses of relevant pre-clinical and clinical data, and to provide results from optimized models to identify the most promising combination regimens for clinical testing |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-22-059.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 343686 Full Announcement-RFA-AI-22-059 -> RFA-AI-22-059-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00276901 | Jan 07, 2023 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00278455 | Jan 07, 2023 | Feb 07, 2023 | View |
Package 1
Mandatory forms
343686 RR_SF424_5_0-5.0.pdf
343686 PHS398_CoverPageSupplement_5_0-5.0.pdf
343686 RR_OtherProjectInfo_1_4-1.4.pdf
343686 PerformanceSite_4_0-4.0.pdf
343686 RR_KeyPersonExpanded_4_0-4.0.pdf
343686 RR_Budget_3_0-3.0.pdf
343686 PHS398_ResearchPlan_4_0-4.0.pdf
343686 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343686 RR_SubawardBudget30_3_0-3.0.pdf
343686 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
343686 RR_SF424_5_0-5.0.pdf
343686 PHS398_CoverPageSupplement_5_0-5.0.pdf
343686 RR_OtherProjectInfo_1_4-1.4.pdf
343686 PerformanceSite_4_0-4.0.pdf
343686 RR_KeyPersonExpanded_4_0-4.0.pdf
343686 RR_Budget_3_0-3.0.pdf
343686 PHS398_ResearchPlan_5_0-5.0.pdf
343686 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343686 RR_SubawardBudget30_3_0-3.0.pdf
343686 PHS_AssignmentRequestForm_3_0-3.0.pdf
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