This grant is for the renewal of the MACS/WIHS Combined Cohort Study (MWCCS) for a six-year period (2026-2032). It aims to continue the follow-up of over 5,600 deeply phenotyped middle-aged and older participants, both living with and without HIV, across the U.S. The study will utilize a ‘populomics’ approach, examining health determinants across multiple scales (e.g., molecular, societal, environmental) using multi-disciplinary methods. The goal is to investigate influences impacting the health, quality of life, and survival of adults living with HIV. This limited competition opportunity is specifically for institutions previously funded under RFA-HL-19-008, seeking to fund up to 13 Clinical Research Sites for the MWCCS.
Opportunity ID: 358275
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-26-009 |
| Funding Opportunity Title: | Limited Competition: Clinical Research Sites (CRS) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 16, 2025 |
| Last Updated Date: | Jan 16, 2025 |
| Original Closing Date for Applications: | May 02, 2025 |
| Current Closing Date for Applications: | May 02, 2025 |
| Archive Date: | Jun 07, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $2,400,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: See NOFO for further eligibility criteria. Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to renew the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 6-year project period (2026-2032). Continuation of this epidemiological cohort study of middle-aged and older people living with HIV (PLWH), along with comparable people living without HIV (PLWOH) will enable the continued follow-up of a deeply phenotyped cohort of more than 5,600 participants from across the United States. This initiative will utilize a populomics approach, i.e., examination of health determinants across multiple scales of influence (e.g. molecular, cellular, physiological, lifestyle/behavioral, household, neighborhood, environmental, cultural, and sociopolitical) using multi-disciplinary methods to investigate the web of influences impacting the health, quality of life, and survival of adults living with HIV. This NOFO is limited to institutions who were funded under RFA-HL-19-008 and will fund up to 13 Clinical Research Sites (CRS) for the MWCCS. This NOFO runs in parallel with two companion U01 NOFOs: RFA-HL-26-010 (Limited Competition: Data Analysis and Sharing Center (DASC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)) and RFA-HL-26-011 (Leadership and Coordination Center (LACC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)). |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-009.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 358275 Full Announcement-RFA-HL-26-009 -> RFA-HL-26-009-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00290172 | Apr 02, 2025 | May 02, 2025 | View |
Package 1
Mandatory forms
358275 RR_SF424_5_0-5.0.pdf
358275 PHS398_CoverPageSupplement_5_0-5.0.pdf
358275 RR_OtherProjectInfo_1_4-1.4.pdf
358275 PerformanceSite_4_0-4.0.pdf
358275 RR_KeyPersonExpanded_4_0-4.0.pdf
358275 RR_Budget10_3_0-3.0.pdf
358275 PHS398_ResearchPlan_5_0-5.0.pdf
358275 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
358275 RR_SubawardBudget10_30_3_0-3.0.pdf
358275 PHS_AssignmentRequestForm_4_0-4.0.pdf
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