The National Heart, Lung, and Blood Institute (NHLBI) offers this grant to renew the MACS/WIHS Combined Cohort Study (MWCCS), an epidemiological study focusing on individuals with and without HIV. This grant supports continued follow-up of approximately 5,500 deeply phenotyped U.S. participants from 2026-2033. It will employ a populomics approach, examining multi-scale health determinants (e.g., molecular to sociopolitical) to understand influences on the well-being and survival of adults living with HIV. This limited competition opportunity funds a single Data Analysis and Sharing Center (DASC) for MWCCS, restricted to institutions previously funded under RFA-HL-19-007.
Opportunity ID: 358278
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-26-010 |
| Funding Opportunity Title: | Limited Competition: Data Analysis and Sharing Center (DASC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 16, 2025 |
| Last Updated Date: | Jan 16, 2025 |
| Original Closing Date for Applications: | May 02, 2025 |
| Current Closing Date for Applications: | May 02, 2025 |
| Archive Date: | Jun 07, 2025 |
| Estimated Total Program Funding: | $2,000,000 |
| Award Ceiling: | $2,000,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: See NOFO for further eligibility criteria. Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to renew the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 7-year project period (2026-2033). Continuation of this epidemiological cohort study of middle-aged and older people living with HIV (PLWH), along with comparable individuals living without HIV (PLWOH) will enable the continued follow-up of a deeply phenotyped cohort of approximately 5,500 participants from across the United States. This initiative will utilize a populomics approach, i.e., examination of health determinants across multiple scales of influence (e.g. molecular, cellular, physiological, lifestyle/behavioral, household, neighborhood, environmental, cultural, and sociopolitical) using multi-disciplinary methods to investigate the web of influences impacting the health, quality of life, and survival of adults living with HIV. This NOFO seeks applications to fund a single Data Analysis and Sharing Center (DASC) for the MWCCS, with competition limited to institutions who were funded under RFA-HL-19-007. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 358278 Full Announcement-RFA-HL-26-010 -> RFA-HL-26-010-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00290175 | Apr 02, 2025 | May 02, 2025 | View |
Package 1
Mandatory forms
358278 RR_SF424_5_0-5.0.pdf
358278 PHS398_CoverPageSupplement_5_0-5.0.pdf
358278 RR_OtherProjectInfo_1_4-1.4.pdf
358278 PerformanceSite_4_0-4.0.pdf
358278 RR_KeyPersonExpanded_4_0-4.0.pdf
358278 RR_Budget10_3_0-3.0.pdf
358278 PHS398_ResearchPlan_5_0-5.0.pdf
358278 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
358278 RR_SubawardBudget10_30_3_0-3.0.pdf
358278 PHS_AssignmentRequestForm_4_0-4.0.pdf
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