The NIH Director’s New Innovator Award Program supports early-stage investigators with exceptional creativity. This grant funds bold, highly innovative research projects poised for major impact on broad NIH mission areas. Applications from diverse backgrounds, including underrepresented groups and various institutions, are strongly encouraged. The program welcomes proposals across all NIH-relevant topics, encompassing behavioral, social, biomedical, applied, and formal sciences, and both basic and clinical research. As a component of the High-Risk, High-Reward Research Program, it complements NIH efforts to empower emerging researchers.
Opportunity ID: 358873
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-25-002 |
| Funding Opportunity Title: | NIH Directors New Innovator Award Program (DP2 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 13, 2025 |
| Last Updated Date: | Jun 13, 2025 |
| Original Closing Date for Applications: | Aug 19, 2025 |
| Current Closing Date for Applications: | Aug 19, 2025 |
| Archive Date: | Sep 24, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $475,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education City or township governments Private institutions of higher education State governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses Small businesses Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NIH Directors New Innovator Award Program supports early stage investigators of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the research workforce. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIHs Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply to this Notice of Funding Opportunity. Applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The NIH Director’s New Innovator Award Program complements other ongoing efforts by NIH and its Institutes and Centers to fund early stage investigators. The NIH Directors New Innovator Award Program is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-25-002.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 358873 Full Announcement-RFA-RM-25-002 -> RFA-RM-25-002-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00290965 | Jul 19, 2025 | Aug 19, 2025 | View |
Package 1
Mandatory forms
358873 RR_SF424_5_0-5.0.pdf
358873 PerformanceSite_4_0-4.0.pdf
358873 RR_OtherProjectInfo_1_4-1.4.pdf
358873 RR_KeyPersonExpanded_4_0-4.0.pdf
358873 PHS398_CoverPageSupplement_5_0-5.0.pdf
358873 PHS398_ResearchPlan_5_0-5.0.pdf
358873 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
358873 PHS_AssignmentRequestForm_4_0-4.0.pdf
358873 RR_Budget10_3_0-3.0.pdf
358873 RR_SubawardBudget10_30_3_0-3.0.pdf
358873 PHS398_ModularBudget_1_2-1.2.pdf
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