This grant is for supporting projects focused on understanding cellular heterogeneity through the transcriptional profiling of individual human cells. Awardees will measure and analyze the distinct transcriptional signatures to define specific cell types and states within various populations. A key component of these projects involves developing and testing innovative methods to accurately detect, analyze, and interpret noise, whether technical or biological in origin. The ultimate goal is to identify strategies that effectively minimize artifactual noise, while simultaneously exploring the crucial biological significance of heterogeneity observed among single cells, advancing our understanding of cellular dynamics and identity.
Opportunity ID: 131873
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-11-013 |
| Funding Opportunity Title: | Studies to evaluate cellular heterogeneity using transcriptional profiling of single cells (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 23, 2011 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 23, 2012 |
| Current Closing Date for Applications: | Jan 23, 2012 |
| Archive Date: | Feb 23, 2012 |
| Estimated Total Program Funding: | $4,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Independent school districts Small businesses County governments Private institutions of higher education Public housing authorities/Indian housing authorities For profit organizations other than small businesses Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity is to support projects to examine the transcriptional signatures of individual human cells in order to measure and analyze cellular heterogeneity and to define specific cell types and/or cell states in a given population.In addition, projects supported through this FOA must devise and test methods to detect, analyze, and interpret noise, which may be technical or biological in origin.These studies will identify methods to minimize artifactual noise while simultaneously exploring the biological significance of heterogeneity among single cells. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-11-013.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.310 | ADOBE-FORMS-B2 | Adobe-Forms-B2 | PKG00086630 | Dec 23, 2011 | Jan 23, 2012 | View |
Package 1
Mandatory forms
131873 RR_SF424_1_2-1.2.pdf
131873 PerformanceSite_1_4-1.4.pdf
131873 RR_OtherProjectInfo_1_3-1.3.pdf
131873 RR_KeyPersonExpanded_1_2-1.2.pdf
131873 PHS398_CoverPageSupplement_1_4-1.4.pdf
131873 PHS398_ResearchPlan_1_3-1.3.pdf
131873 PHS398_Checklist_1_3-1.3.pdf
Optional forms
131873 RR_SubawardBudget30-1.2.pdf
131873 PHS398_ModularBudget_1_2-1.2.pdf
131873 RR_Budget-1.1.pdf
131873 PHS_CoverLetter_1_2-1.2.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
