This National Institutes of Health (NIH) grant from the National Cancer Institute (NCI) is for exploratory research focused on advancing and validating emerging technologies that enhance the quality of biospecimens used in cancer research and clinical care. It aims to address pre-analytical degradation issues during sample collection, processing, handling, and storage. The R33 mechanism supports projects where initial feasibility is proven, but further development and rigorous validation are needed to ensure broad adoption by the research community. The overall purpose is to fund innovative tools, devices, instrumentation, and methods designed to preserve sample integrity or establish robust quality assessment criteria. These technologies are expected to significantly accelerate and improve various aspects of cancer research by minimizing pre-analytical variations affecting sample utility.
Opportunity ID: 344759
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-23-005 |
| Funding Opportunity Title: | Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.394 — Cancer Detection and Diagnosis Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 02, 2022 |
| Last Updated Date: | Dec 02, 2022 |
| Original Closing Date for Applications: | Sep 01, 2023 |
| Current Closing Date for Applications: | Sep 01, 2023 |
| Archive Date: | Oct 07, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public housing authorities/Indian housing authorities Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education County governments For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) solicits grant applications proposing exploratory research projects focused on further development and validation of emerging technologies that improve the quality of the samples used for cancer research or clinical care. This includes new capabilities to address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and/or storage of cancer-relevant biospecimens. This FOA solicits R33 applications where major feasibility gaps for the technology or methodology have been overcome, as demonstrated with supportive preliminary data, but still requires further development and rigorous validation to encourage adoption by the research community. The overall goal is to support the development of highly innovative technologies capable of maximizing or otherwise interrogating the quality and utility of biological samples used for downstream analyses. This FOA will support the development of tools, devices, instrumentation, and associated methods to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection and screening, clinical diagnosis, treatment, epidemiology, or address issues associated with cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-23-005.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00278764 | Feb 01, 2023 | Sep 01, 2023 | View |
Package 1
Mandatory forms
344759 RR_SF424_5_0-5.0.pdf
344759 PHS398_CoverPageSupplement_5_0-5.0.pdf
344759 RR_OtherProjectInfo_1_4-1.4.pdf
344759 PerformanceSite_4_0-4.0.pdf
344759 RR_KeyPersonExpanded_4_0-4.0.pdf
344759 RR_Budget_3_0-3.0.pdf
344759 PHS398_ResearchPlan_5_0-5.0.pdf
344759 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
344759 RR_SubawardBudget30_3_0-3.0.pdf
344759 PHS_AssignmentRequestForm_3_0-3.0.pdf
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