This NIH Department grant aims to fund basic research exploring the complex interplay between HIV infection and substance use. The focus is on identifying signaling pathways, HIV-host protein interactions, and post-translational modifications that lead to changes in brain function, neuropathological alterations, and neurocognitive dysfunctions. A key objective is to understand how addictive drugs and HIV converge to induce these central nervous system (CNS) impacts. Furthermore, the grant seeks to advance the discovery and development of novel chemical and biological strategies. These strategies are intended for the prevention or mitigation of CNS complications stemming from both HIV infection and substance use disorders, ultimately improving neurological outcomes in affected individuals.
Opportunity ID: 344956
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-24-014 |
| Funding Opportunity Title: | Mechanisms and Targets at the Intersection of HIV and Substance Use (R21 Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 16, 2022 |
| Last Updated Date: | Dec 16, 2022 |
| Original Closing Date for Applications: | Aug 09, 2023 |
| Current Closing Date for Applications: | Aug 09, 2023 |
| Archive Date: | Sep 14, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $275,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Private institutions of higher education For profit organizations other than small businesses County governments State governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education Independent school districts Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this FOA is to support basic research on signaling pathways and mechanisms including HIV-host protein interactions and post-translational modifications by which addictive drugs and HIV infection converge to induce changes in brain function and cause neuropathological alterations and neurocognitive dysfunctions. This FOA also aims to promote discovery and development of novel chemical and biological approaches for prevention or mitigation of CNS complications associated with HIV infection and substance use disorders. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-24-014.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 344956 Full Announcement-RFA-DA-24-014 -> RFA-DA-24-014-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00278950 | Jul 09, 2023 | Aug 09, 2023 | View |
Package 1
Mandatory forms
344956 RR_SF424_5_0-5.0.pdf
344956 PHS398_CoverPageSupplement_5_0-5.0.pdf
344956 RR_OtherProjectInfo_1_4-1.4.pdf
344956 PerformanceSite_4_0-4.0.pdf
344956 RR_KeyPersonExpanded_4_0-4.0.pdf
344956 PHS398_ResearchPlan_5_0-5.0.pdf
344956 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
344956 RR_Budget_3_0-3.0.pdf
344956 RR_SubawardBudget30_3_0-3.0.pdf
344956 PHS398_ModularBudget_1_2-1.2.pdf
344956 PHS_AssignmentRequestForm_3_0-3.0.pdf
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