This grant is for broad, interdisciplinary research focusing on the ecological, evolutionary, organismal, and social drivers influencing infectious disease transmission dynamics. It seeks to advance quantitative, mathematical, or computational understanding of pathogen dynamics, aiming to discover principles of disease emergence and transmission and test predictive models. Projects should explore determinants and interactions across all host species, including humans, animals, and plants. Research may encompass diverse pathogen types—zoonotic, vector-borne, environmentally-borne, enteric, or respiratory—across terrestrial, aquatic, or marine systems. Proposals addressing diseases of concern in Low- or Middle-Income Countries (LMICs) and agricultural systems are particularly encouraged. Multidisciplinary teams are key to integrating knowledge and enhancing disease prediction and control.
Opportunity ID: 359562
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | 23-616 |
| Funding Opportunity Title: | Ecology and Evolution of Infectious Diseases |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 10.310 — Agriculture and Food Research Initiative (AFRI) |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 06, 2025 |
| Last Updated Date: | Jun 06, 2025 |
| Original Closing Date for Applications: | – Opportunity is Archived |
| Current Closing Date for Applications: | – Opportunity is Archived |
| Archive Date: | Jun 07, 2025 |
| Estimated Total Program Funding: | $36,000,000 |
| Award Ceiling: | $3,000,000 |
| Award Floor: | $1,500,000 |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | *Who May Submit Proposals: Proposals may only be submitted by the following: -For-profit organizations: U.S.-based commercial organizations, including small businesses, with strong capabilities in scientific or engineering research or education and a passion for innovation. -Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities. -Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus. -Tribal Nations: An American Indian or Alaska Native tribe, band, nation, pueblo, village, or community that the Secretary of the Interior acknowledges as a federally recognized tribe pursuant to the Federally Recognized Indian Tribe List Act of 1994, 25 U.S.C. §§ 5130-5131. |
Additional Information
| Agency Name: | U.S. National Science Foundation |
| Description: | The multi-agency Ecology and Evolution of Infectious Diseases program supports research on the ecological, evolutionary, organismal, and social drivers that influence the transmission dynamics of infectious diseases. The central theme of submitted projects must be the quantitative, mathematical, or computational understanding of pathogen transmission dynamics. The intent is discovery of principles of infectious disease (re)emergence and transmission and testing mathematical or computational models that elucidate infectious disease systems. Projects should be broad, interdisciplinary efforts that go beyond the scope of typical studies. They should focus on the determinants and interactions of (re)emergence and transmission among any host species, including but not limited to humans, non-human animals, and/or plants. This includes, for example, the spread of pathogens; the influence of environmental factors such as climate; the population dynamics and genetics of vectors and reservoir species or hosts; how the physiology or behavior of the pathogen, vector, or host species biology affects transmission dynamics; the feedback between ecological transmission and evolutionary dynamics; and the cultural, social, behavioral, and economic dimensions of pathogen transmission and disease. Research may be on zoonotic, environmentally-borne, vector-borne, enteric, or respiratory pathogens of either terrestrial, aquatic, or marine systems and organisms, including diseases of animals and plants, at any scale from specific pathogens to inclusive environmental systems. Proposals for research on disease systems of public health concern toLow- or Middle-Income Countries (LMICs) are strongly encouraged, as are disease systems of concern in agricultural systems. Investigators are encouraged to develop the appropriate multidisciplinary team, including for example, anthropologists, modelers, ecologists, bioinformaticians, genomics researchers, social scientists, economists, oceanographers, mathematical scientists, behaviorists, epidemiologists, evolutionary biologists, entomologists, immunologists, parasitologists, microbiologists, bacteriologists, virologists, pathologists or veterinarians, with the goal of integrating knowledge across disciplines to enhance our ability to predict and control infectious diseases. |
| Link to Additional Information: | NSF Publication 23-616 |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NSF grants.gov support
grantsgovsupport@nsf.gov Email:grantsgovsupport@nsf.gov |
Version History
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