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Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed)

Opportunity ID: 361833

General Information

Funding Opportunity Number RFA-AI-27-014
Funding Opportunity Title Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed)
Agency National Institutes of Health
Document Type synopsis
Version 1
Opportunity Category Discretionary
Opportunity Category Explanation Not specified
Funding Instrument Type Cooperative Agreement
Category of Funding Activity Health
Category Explanation Not specified
Expected Number of Awards Not specified
Cost Sharing or Matching Requirement No
Posted Date Sep 01, 2026 12:00:00 AM EDT
Last Updated Date Sep 01, 2026 07:55:04 AM EDT
Original Closing Date Oct 09, 2028 12:00:00 AM EDT
Original Closing Date Notes Not specified
Current Closing Date Oct 09, 2028 12:00:00 AM EDT
Current Closing Date Notes Not specified
Estimated Synopsis Date Not specified
Estimated Application Due Date Not specified
Estimated Award Date Not specified
Estimated Project Start Date Not specified
Archive Date Dec 08, 2028 12:00:00 AM EST
Estimated Total Program Funding Not specified
Award Ceiling none
Award Floor none

Assistance Listings

  • 93.233 — National Center on Sleep Disorders Research
  • 93.279 — Drug Use and Addiction Research Programs
  • 93.837 — Cardiovascular Diseases Research
  • 93.838 — Lung Diseases Research
  • 93.839 — Blood Diseases and Resources Research
  • 93.840 — Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
  • 93.846 — Arthritis, Musculoskeletal and Skin Diseases Research
  • 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders
  • 93.855 — Allergy and Infectious Diseases Research
  • 93.867 — Vision Research

Eligibility

Eligible Applicants City or township governments; County governments; Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; Independent school districts; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Special district governments; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Description

The purpose of this notice of funding opportunity (NOFO) is to support research that advances understanding of the natural history of radiation or chemical exposures; develops relevant injury models; identifies and validates diagnostic tools, biomarkers, or triage technologies; and supports the development of effective medical countermeasures (MCMs) to mitigate or treat acute and/or delayed injuries resulting from radiological/nuclear or chemical public health emergencies.

Additional Information

Contact National Institutes of Health
Contact Information National Institute of Allergy and Infectious Diseases (NIAID)
RADCHEM_U01@mail.nih.gov
Email RADCHEM_U01@mail.nih.gov
Email Description RADCHEM_U01@mail.nih.gov
Phone 301-402-2541

Additional information

Version History

Version history

Opp hist id / Opportunity id 361833
Opp hist id / Revision 0
Opportunity id 361833
Revision 0
Opportunity number RFA-AI-27-014
Opportunity title Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Chemical or Radiation/Nuclear (CRN) Threats
Owning agency code HHS-NIH11
Opportunity category / Category D
Opportunity category / Description Discretionary
Forecast / Opp hist id / Opportunity id 361833
Forecast / Opp hist id / Revision 0
Forecast / Opportunity id 361833
Forecast / Revision 0
Forecast / Version 1
Forecast / Posting date Apr 09, 2026 12:00:00 AM EDT
Forecast / Forecast desc The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the NIH mission by supporting research on concepts and technologies to address civilian radiation or chemical threats. Research is administered by NIAID on behalf of NIH via the Radiation and Nuclear (RNCP), and the Chemical Countermeasures (CCRP) Research Programs. A shared congressional mandate to the NIH OD (119 Stat. 2850; Public Law 109-149-Dec. 30, 2005), supports research to develop new ideas and technologies to diagnose, mitigate, and treat acute and delayed effects of radiation or chemical exposures during and after a public health emergency.
RNCP: Supports development of radiation-focused models, biomarkers of damage, devices to assess and predict injury, and products to improve survival and reduce morbidity across multiple organ systems.
CCRP: Supports preclinical work on products to mitigate and treat injuries after exposure to government-designated Chemicals of Concern. Candidates with efficacy in a post-exposure, civilian mass casualty setting are sought.
Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Forecast / Cost sharing No
Forecast / Agency contact name National Institute of Allergy and Infectious Diseases (NIAID)
Forecast / Agency contact phone Please contact via e-mail.
Forecast / Agency contact email RADCHEM_U01@mail.nih.gov
Forecast / Agency contact email desc RADCHEM_U01@mail.nih.gov
Forecast / Agency code HHS-NIH11
Forecast / Applicant eligibility desc Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
Forecast / Est synopsis posting date Jul 10, 2026 12:00:00 AM EDT
Forecast / Est application response date Oct 09, 2026 12:00:00 AM EDT
Forecast / Est award date Jul 01, 2027 12:00:00 AM EDT
Forecast / Est project start date Jul 01, 2027 12:00:00 AM EDT
Forecast / Fiscal year 2027
Forecast / Create time stamp Apr 09, 2026 03:29:59 PM EDT
Forecast / Action type U
Forecast / Action date Aug 31, 2026 09:29:08 AM EDT
Forecast / Created date Apr 09, 2026 03:29:59 PM EDT
Forecast / Last updated date Apr 09, 2026 03:29:59 PM EDT
Forecast / Agency details / Code NIH
Forecast / Agency details / Seed HHS-NIH11
Forecast / Agency details / Agency name National Institutes of Health
Forecast / Agency details / Agency code HHS-NIH11
Forecast / Agency details / Top agency code HHS
Forecast / Applicant types 1 / Id 05
Forecast / Applicant types 1 / Description Independent school districts
Forecast / Applicant types 2 / Id 01
Forecast / Applicant types 2 / Description County governments
Forecast / Applicant types 3 / Id 04
Forecast / Applicant types 3 / Description Special district governments
Forecast / Applicant types 4 / Id 20
Forecast / Applicant types 4 / Description Private institutions of higher education
Forecast / Applicant types 5 / Id 23
Forecast / Applicant types 5 / Description Small businesses
Forecast / Applicant types 6 / Id 08
Forecast / Applicant types 6 / Description Public housing authorities/Indian housing authorities
Forecast / Applicant types 7 / Id 07
Forecast / Applicant types 7 / Description Native American tribal governments (Federally recognized)
Forecast / Applicant types 8 / Id 02
Forecast / Applicant types 8 / Description City or township governments
Forecast / Applicant types 9 / Id 22
Forecast / Applicant types 9 / Description For profit organizations other than small businesses
Forecast / Applicant types 10 / Id 25
Forecast / Applicant types 10 / Description Others (see text field entitled "Additional Information on Eligibility" for clarification)
Forecast / Applicant types 11 / Id 11
Forecast / Applicant types 11 / Description Native American tribal organizations (other than Federally recognized tribal governments)
Forecast / Applicant types 12 / Id 06
Forecast / Applicant types 12 / Description Public and State controlled institutions of higher education
Forecast / Applicant types 13 / Id 12
Forecast / Applicant types 13 / Description Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Forecast / Applicant types 14 / Id 13
Forecast / Applicant types 14 / Description Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Forecast / Applicant types 15 / Id 00
Forecast / Applicant types 15 / Description State governments
Forecast / Funding instruments 1 / Id CA
Forecast / Funding instruments 1 / Description Cooperative Agreement
Forecast / Funding activity categories 1 / Id HL
Forecast / Funding activity categories 1 / Description Health
Forecast / Posting date str 2026-04-09-00-00-00
Forecast / Est synopsis posting date str 2026-07-10-00-00-00
Forecast / Est application response date str 2026-10-09-00-00-00
Forecast / Est award date str 2027-07-01-00-00-00
Forecast / Est project start date str 2027-07-01-00-00-00
Forecast / Create time stamp str 2026-04-09-15-29-59
Cfdas 1 / Id 432623
Cfdas 1 / Opportunity id 361833
Cfdas 1 / Revision 2
Cfdas 1 / Cfda number 93.279
Cfdas 1 / Program title Drug Use and Addiction Research Programs
Cfdas 2 / Id 432621
Cfdas 2 / Opportunity id 361833
Cfdas 2 / Revision 2
Cfdas 2 / Cfda number 93.846
Cfdas 2 / Program title Arthritis, Musculoskeletal and Skin Diseases Research
Cfdas 3 / Id 432620
Cfdas 3 / Opportunity id 361833
Cfdas 3 / Revision 2
Cfdas 3 / Cfda number 93.853
Cfdas 3 / Program title Extramural Research Programs in the Neurosciences and Neurological Disorders
Cfdas 4 / Id 432624
Cfdas 4 / Opportunity id 361833
Cfdas 4 / Revision 2
Cfdas 4 / Cfda number 93.855
Cfdas 4 / Program title Allergy and Infectious Diseases Research
Cfdas 5 / Id 432622
Cfdas 5 / Opportunity id 361833
Cfdas 5 / Revision 2
Cfdas 5 / Cfda number 93.867
Cfdas 5 / Program title Vision Research
Synopsis modified fields Not specified
Forecast modified fields Not specified
Opp hist id / Opportunity id 361833
Opp hist id / Revision 1
Opportunity id 361833
Revision 1
Opportunity number RFA-AI-27-014
Opportunity title Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed)
Owning agency code HHS-NIH11
Opportunity category / Category D
Opportunity category / Description Discretionary
Modified comments Updated details to match current NOFO.
Forecast / Opp hist id / Opportunity id 361833
Forecast / Opp hist id / Revision 1
Forecast / Opportunity id 361833
Forecast / Revision 1
Forecast / Version 2
Forecast / Posting date Apr 09, 2026 12:00:00 AM EDT
Forecast / Forecast desc The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the NIH mission by supporting research on concepts and technologies to address civilian radiation or chemical threats. Research is administered by NIAID on behalf of NIH via the Radiation and Nuclear (RNCP), and the Chemical Countermeasures (CCRP) Research Programs. A shared congressional mandate to the NIH OD (119 Stat. 2850; Public Law 109-149-Dec. 30, 2005), supports research to develop new ideas and technologies to diagnose, mitigate, and treat acute and delayed effects of radiation or chemical exposures during and after a public health emergency.
RNCP: Supports development of radiation-focused models, biomarkers of damage, devices to assess and predict injury, and products to improve survival and reduce morbidity across multiple organ systems.
CCRP: Supports preclinical work on products to mitigate and treat injuries after exposure to government-designated Chemicals of Concern. Candidates with efficacy in a post-exposure, civilian mass casualty setting are sought.
Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Forecast / Cost sharing No
Forecast / Agency contact name National Institute of Allergy and Infectious Diseases (NIAID)
Forecast / Agency contact phone Please contact via e-mail.
Forecast / Agency contact email RADCHEM_U01@mail.nih.gov
Forecast / Agency contact email desc RADCHEM_U01@mail.nih.gov
Forecast / Agency code HHS-NIH11
Forecast / Applicant eligibility desc Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
Forecast / Est synopsis posting date Jul 10, 2026 12:00:00 AM EDT
Forecast / Est application response date Oct 09, 2026 12:00:00 AM EDT
Forecast / Est award date Jul 01, 2027 12:00:00 AM EDT
Forecast / Est project start date Jul 01, 2027 12:00:00 AM EDT
Forecast / Fiscal year 2027
Forecast / Mod comments Updated details to match current NOFO.
Forecast / Create time stamp Aug 31, 2026 09:29:08 AM EDT
Forecast / Action type U
Forecast / Action date Sep 01, 2026 07:55:04 AM EDT
Forecast / Created date Apr 09, 2026 03:29:59 PM EDT
Forecast / Last updated date Aug 31, 2026 09:29:08 AM EDT
Forecast / Agency details / Code NIH
Forecast / Agency details / Seed HHS-NIH11
Forecast / Agency details / Agency name National Institutes of Health
Forecast / Agency details / Agency code HHS-NIH11
Forecast / Agency details / Top agency code HHS
Forecast / Applicant types 1 / Id 05
Forecast / Applicant types 1 / Description Independent school districts
Forecast / Applicant types 2 / Id 01
Forecast / Applicant types 2 / Description County governments
Forecast / Applicant types 3 / Id 04
Forecast / Applicant types 3 / Description Special district governments
Forecast / Applicant types 4 / Id 20
Forecast / Applicant types 4 / Description Private institutions of higher education
Forecast / Applicant types 5 / Id 23
Forecast / Applicant types 5 / Description Small businesses
Forecast / Applicant types 6 / Id 08
Forecast / Applicant types 6 / Description Public housing authorities/Indian housing authorities
Forecast / Applicant types 7 / Id 07
Forecast / Applicant types 7 / Description Native American tribal governments (Federally recognized)
Forecast / Applicant types 8 / Id 02
Forecast / Applicant types 8 / Description City or township governments
Forecast / Applicant types 9 / Id 22
Forecast / Applicant types 9 / Description For profit organizations other than small businesses
Forecast / Applicant types 10 / Id 25
Forecast / Applicant types 10 / Description Others (see text field entitled "Additional Information on Eligibility" for clarification)
Forecast / Applicant types 11 / Id 11
Forecast / Applicant types 11 / Description Native American tribal organizations (other than Federally recognized tribal governments)
Forecast / Applicant types 12 / Id 06
Forecast / Applicant types 12 / Description Public and State controlled institutions of higher education
Forecast / Applicant types 13 / Id 12
Forecast / Applicant types 13 / Description Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Forecast / Applicant types 14 / Id 13
Forecast / Applicant types 14 / Description Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Forecast / Applicant types 15 / Id 00
Forecast / Applicant types 15 / Description State governments
Forecast / Funding instruments 1 / Id CA
Forecast / Funding instruments 1 / Description Cooperative Agreement
Forecast / Funding activity categories 1 / Id HL
Forecast / Funding activity categories 1 / Description Health
Forecast / Posting date str 2026-04-09-00-00-00
Forecast / Est synopsis posting date str 2026-07-10-00-00-00
Forecast / Est application response date str 2026-10-09-00-00-00
Forecast / Est award date str 2027-07-01-00-00-00
Forecast / Est project start date str 2027-07-01-00-00-00
Forecast / Create time stamp str 2026-08-31-09-29-08
Cfdas 1 / Id 432623
Cfdas 1 / Opportunity id 361833
Cfdas 1 / Revision 2
Cfdas 1 / Cfda number 93.279
Cfdas 1 / Program title Drug Use and Addiction Research Programs
Cfdas 2 / Id 432621
Cfdas 2 / Opportunity id 361833
Cfdas 2 / Revision 2
Cfdas 2 / Cfda number 93.846
Cfdas 2 / Program title Arthritis, Musculoskeletal and Skin Diseases Research
Cfdas 3 / Id 432620
Cfdas 3 / Opportunity id 361833
Cfdas 3 / Revision 2
Cfdas 3 / Cfda number 93.853
Cfdas 3 / Program title Extramural Research Programs in the Neurosciences and Neurological Disorders
Cfdas 4 / Id 432624
Cfdas 4 / Opportunity id 361833
Cfdas 4 / Revision 2
Cfdas 4 / Cfda number 93.855
Cfdas 4 / Program title Allergy and Infectious Diseases Research
Cfdas 5 / Id 432622
Cfdas 5 / Opportunity id 361833
Cfdas 5 / Revision 2
Cfdas 5 / Cfda number 93.867
Cfdas 5 / Program title Vision Research
Synopsis modified fields Not specified
Forecast modified fields revision; version; opportunityTitle; sendEmail; modComments; createTimeStamp
Opp hist id / Opportunity id 361833
Opp hist id / Revision 3
Opportunity id 361833
Revision 3
Opportunity number RFA-AI-27-014
Opportunity title Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed)
Owning agency code HHS-NIH11
Opportunity category / Category D
Opportunity category / Description Discretionary
Modified comments Updated details to match current NOFO.
Forecast / Opp hist id / Opportunity id 361833
Forecast / Opp hist id / Revision 3
Forecast / Opportunity id 361833
Forecast / Revision 3
Forecast / Version 3
Forecast / Posting date Apr 09, 2026 12:00:00 AM EDT
Forecast / Forecast desc The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the NIH mission by supporting research on concepts and technologies to address civilian radiation or chemical threats. Research is administered by NIAID on behalf of NIH via the Radiation and Nuclear (RNCP), and the Chemical Countermeasures (CCRP) Research Programs. A shared congressional mandate to the NIH OD (119 Stat. 2850; Public Law 109-149-Dec. 30, 2005), supports research to develop new ideas and technologies to diagnose, mitigate, and treat acute and delayed effects of radiation or chemical exposures during and after a public health emergency.
RNCP: Supports development of radiation-focused models, biomarkers of damage, devices to assess and predict injury, and products to improve survival and reduce morbidity across multiple organ systems.
CCRP: Supports preclinical work on products to mitigate and treat injuries after exposure to government-designated Chemicals of Concern. Candidates with efficacy in a post-exposure, civilian mass casualty setting are sought.
Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Forecast / Cost sharing No
Forecast / Agency contact name National Institute of Allergy and Infectious Diseases (NIAID)
Forecast / Agency contact phone Please contact via e-mail.
Forecast / Agency contact email RADCHEM_U01@mail.nih.gov
Forecast / Agency contact email desc RADCHEM_U01@mail.nih.gov
Forecast / Agency code HHS-NIH11
Forecast / Applicant eligibility desc Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
Forecast / Est synopsis posting date Jul 10, 2026 12:00:00 AM EDT
Forecast / Est application response date Oct 09, 2026 12:00:00 AM EDT
Forecast / Est award date Jul 01, 2027 12:00:00 AM EDT
Forecast / Est project start date Jul 01, 2027 12:00:00 AM EDT
Forecast / Fiscal year 2027
Forecast / Mod comments Updated details to match current NOFO.
Forecast / Create time stamp Sep 01, 2026 07:55:04 AM EDT
Forecast / Action type U
Forecast / Action date Sep 01, 2026 07:55:05 AM EDT
Forecast / Created date Apr 09, 2026 03:29:59 PM EDT
Forecast / Last updated date Sep 01, 2026 07:55:04 AM EDT
Forecast / Agency details / Code NIH
Forecast / Agency details / Seed HHS-NIH11
Forecast / Agency details / Agency name National Institutes of Health
Forecast / Agency details / Agency code HHS-NIH11
Forecast / Agency details / Top agency code HHS
Forecast / Applicant types 1 / Id 05
Forecast / Applicant types 1 / Description Independent school districts
Forecast / Applicant types 2 / Id 01
Forecast / Applicant types 2 / Description County governments
Forecast / Applicant types 3 / Id 04
Forecast / Applicant types 3 / Description Special district governments
Forecast / Applicant types 4 / Id 20
Forecast / Applicant types 4 / Description Private institutions of higher education
Forecast / Applicant types 5 / Id 23
Forecast / Applicant types 5 / Description Small businesses
Forecast / Applicant types 6 / Id 08
Forecast / Applicant types 6 / Description Public housing authorities/Indian housing authorities
Forecast / Applicant types 7 / Id 07
Forecast / Applicant types 7 / Description Native American tribal governments (Federally recognized)
Forecast / Applicant types 8 / Id 02
Forecast / Applicant types 8 / Description City or township governments
Forecast / Applicant types 9 / Id 22
Forecast / Applicant types 9 / Description For profit organizations other than small businesses
Forecast / Applicant types 10 / Id 25
Forecast / Applicant types 10 / Description Others (see text field entitled "Additional Information on Eligibility" for clarification)
Forecast / Applicant types 11 / Id 11
Forecast / Applicant types 11 / Description Native American tribal organizations (other than Federally recognized tribal governments)
Forecast / Applicant types 12 / Id 06
Forecast / Applicant types 12 / Description Public and State controlled institutions of higher education
Forecast / Applicant types 13 / Id 12
Forecast / Applicant types 13 / Description Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Forecast / Applicant types 14 / Id 13
Forecast / Applicant types 14 / Description Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Forecast / Applicant types 15 / Id 00
Forecast / Applicant types 15 / Description State governments
Forecast / Funding instruments 1 / Id CA
Forecast / Funding instruments 1 / Description Cooperative Agreement
Forecast / Funding activity categories 1 / Id HL
Forecast / Funding activity categories 1 / Description Health
Forecast / Posting date str 2026-04-09-00-00-00
Forecast / Est synopsis posting date str 2026-07-10-00-00-00
Forecast / Est application response date str 2026-10-09-00-00-00
Forecast / Est award date str 2027-07-01-00-00-00
Forecast / Est project start date str 2027-07-01-00-00-00
Forecast / Create time stamp str 2026-09-01-07-55-04
Cfdas 1 / Id 435276
Cfdas 1 / Opportunity id 361833
Cfdas 1 / Revision 2
Cfdas 1 / Cfda number 93.233
Cfdas 1 / Program title National Center on Sleep Disorders Research
Cfdas 2 / Id 432623
Cfdas 2 / Opportunity id 361833
Cfdas 2 / Revision 2
Cfdas 2 / Cfda number 93.279
Cfdas 2 / Program title Drug Use and Addiction Research Programs
Cfdas 3 / Id 435275
Cfdas 3 / Opportunity id 361833
Cfdas 3 / Revision 2
Cfdas 3 / Cfda number 93.837
Cfdas 3 / Program title Cardiovascular Diseases Research
Cfdas 4 / Id 435278
Cfdas 4 / Opportunity id 361833
Cfdas 4 / Revision 2
Cfdas 4 / Cfda number 93.838
Cfdas 4 / Program title Lung Diseases Research
Cfdas 5 / Id 435277
Cfdas 5 / Opportunity id 361833
Cfdas 5 / Revision 2
Cfdas 5 / Cfda number 93.839
Cfdas 5 / Program title Blood Diseases and Resources Research
Cfdas 6 / Id 435279
Cfdas 6 / Opportunity id 361833
Cfdas 6 / Revision 2
Cfdas 6 / Cfda number 93.840
Cfdas 6 / Program title Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
Cfdas 7 / Id 432621
Cfdas 7 / Opportunity id 361833
Cfdas 7 / Revision 2
Cfdas 7 / Cfda number 93.846
Cfdas 7 / Program title Arthritis, Musculoskeletal and Skin Diseases Research
Cfdas 8 / Id 432620
Cfdas 8 / Opportunity id 361833
Cfdas 8 / Revision 2
Cfdas 8 / Cfda number 93.853
Cfdas 8 / Program title Extramural Research Programs in the Neurosciences and Neurological Disorders
Cfdas 9 / Id 432624
Cfdas 9 / Opportunity id 361833
Cfdas 9 / Revision 2
Cfdas 9 / Cfda number 93.855
Cfdas 9 / Program title Allergy and Infectious Diseases Research
Cfdas 10 / Id 432622
Cfdas 10 / Opportunity id 361833
Cfdas 10 / Revision 2
Cfdas 10 / Cfda number 93.867
Cfdas 10 / Program title Vision Research
Synopsis modified fields Not specified
Forecast modified fields revision; version; cfdas; sendEmail; createTimeStamp

Forecast changes

revision

version

archiveDate

modComments

Id 361833
Revision 4
Opportunity number RFA-AI-27-014
Opportunity title Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed)
Owning agency code HHS-NIH11
Modified comments Updated details to match current NOFO.
Opportunity category / Category D
Opportunity category / Description Discretionary
Synopsis / Opportunity id 361833
Synopsis / Version 1
Synopsis / Agency code HHS-NIH11
Synopsis / Agency name National Institutes of Health
Synopsis / Agency phone 301-402-2541
Synopsis / Agency address desc RADCHEM_U01@mail.nih.gov
Synopsis / Agency details / Code NIH
Synopsis / Agency details / Seed HHS-NIH11
Synopsis / Agency details / Agency name National Institutes of Health
Synopsis / Agency details / Agency code HHS-NIH11
Synopsis / Agency details / Top agency code HHS
Synopsis / Top agency details / Code HHS
Synopsis / Top agency details / Seed HHS
Synopsis / Top agency details / Agency name Department of Health and Human Services
Synopsis / Top agency details / Agency code HHS
Synopsis / Top agency details / Top agency code HHS
Synopsis / Agency contact phone 301-402-2541
Synopsis / Agency contact name National Institutes of Health
Synopsis / Agency contact desc National Institute of Allergy and Infectious Diseases (NIAID)
RADCHEM_U01@mail.nih.gov
Synopsis / Agency contact email RADCHEM_U01@mail.nih.gov
Synopsis / Agency contact email desc RADCHEM_U01@mail.nih.gov
Synopsis / Synopsis desc The purpose of this notice of funding opportunity (NOFO) is to support research that advances understanding of the natural history of radiation or chemical exposures; develops relevant injury models; identifies and validates diagnostic tools, biomarkers, or triage technologies; and supports the development of effective medical countermeasures (MCMs) to mitigate or treat acute and/or delayed injuries resulting from radiological/nuclear or chemical public health emergencies.
Synopsis / Response date Oct 09, 2028 12:00:00 AM EDT
Synopsis / Posting date Sep 01, 2026 12:00:00 AM EDT
Synopsis / Archive date Dec 08, 2028 12:00:00 AM EST
Synopsis / Cost sharing No
Synopsis / Award ceiling none
Synopsis / Award floor none
Synopsis / Applicant eligibility desc Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.
Synopsis / Create time stamp Sep 01, 2026 07:55:14 AM EDT
Synopsis / Created date Sep 01, 2026 07:55:05 AM EDT
Synopsis / Last updated date Sep 01, 2026 07:55:04 AM EDT
Synopsis / Applicant types 1 / Id 02
Synopsis / Applicant types 1 / Description City or township governments
Synopsis / Applicant types 2 / Id 01
Synopsis / Applicant types 2 / Description County governments
Synopsis / Applicant types 3 / Id 11
Synopsis / Applicant types 3 / Description Native American tribal organizations (other than Federally recognized tribal governments)
Synopsis / Applicant types 4 / Id 06
Synopsis / Applicant types 4 / Description Public and State controlled institutions of higher education
Synopsis / Applicant types 5 / Id 05
Synopsis / Applicant types 5 / Description Independent school districts
Synopsis / Applicant types 6 / Id 07
Synopsis / Applicant types 6 / Description Native American tribal governments (Federally recognized)
Synopsis / Applicant types 7 / Id 08
Synopsis / Applicant types 7 / Description Public housing authorities/Indian housing authorities
Synopsis / Applicant types 8 / Id 23
Synopsis / Applicant types 8 / Description Small businesses
Synopsis / Applicant types 9 / Id 13
Synopsis / Applicant types 9 / Description Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Synopsis / Applicant types 10 / Id 00
Synopsis / Applicant types 10 / Description State governments
Synopsis / Applicant types 11 / Id 04
Synopsis / Applicant types 11 / Description Special district governments
Synopsis / Applicant types 12 / Id 22
Synopsis / Applicant types 12 / Description For profit organizations other than small businesses
Synopsis / Applicant types 13 / Id 25
Synopsis / Applicant types 13 / Description Others (see text field entitled "Additional Information on Eligibility" for clarification)
Synopsis / Applicant types 14 / Id 12
Synopsis / Applicant types 14 / Description Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Synopsis / Applicant types 15 / Id 20
Synopsis / Applicant types 15 / Description Private institutions of higher education
Synopsis / Funding instruments 1 / Id CA
Synopsis / Funding instruments 1 / Description Cooperative Agreement
Synopsis / Funding activity categories 1 / Id HL
Synopsis / Funding activity categories 1 / Description Health
Synopsis / Response date str 2028-10-09-00-00-00
Synopsis / Posting date str 2026-09-01-00-00-00
Synopsis / Archive date str 2028-12-08-00-00-00
Synopsis / Create time stamp str 2026-09-01-07-55-14
Agency details / Code NIH
Agency details / Seed HHS-NIH11
Agency details / Agency name National Institutes of Health
Agency details / Agency code HHS-NIH11
Agency details / Top agency code HHS
Top agency details / Code HHS
Top agency details / Seed HHS
Top agency details / Agency name Department of Health and Human Services
Top agency details / Agency code HHS
Top agency details / Top agency code HHS
Forecast / Opportunity id 361833
Forecast / Version 4
Forecast / Posting date Apr 09, 2026 12:00:00 AM EDT
Forecast / Archive date Aug 31, 2026 12:00:00 AM EDT
Forecast / Forecast desc The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the NIH mission by supporting research on concepts and technologies to address civilian radiation or chemical threats. Research is administered by NIAID on behalf of NIH via the Radiation and Nuclear (RNCP), and the Chemical Countermeasures (CCRP) Research Programs. A shared congressional mandate to the NIH OD (119 Stat. 2850; Public Law 109-149-Dec. 30, 2005), supports research to develop new ideas and technologies to diagnose, mitigate, and treat acute and delayed effects of radiation or chemical exposures during and after a public health emergency.
RNCP: Supports development of radiation-focused models, biomarkers of damage, devices to assess and predict injury, and products to improve survival and reduce morbidity across multiple organ systems.
CCRP: Supports preclinical work on products to mitigate and treat injuries after exposure to government-designated Chemicals of Concern. Candidates with efficacy in a post-exposure, civilian mass casualty setting are sought.
Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Forecast / Cost sharing No
Forecast / Agency contact name National Institute of Allergy and Infectious Diseases (NIAID)
Forecast / Agency contact phone Please contact via e-mail.
Forecast / Agency contact email RADCHEM_U01@mail.nih.gov
Forecast / Agency contact email desc RADCHEM_U01@mail.nih.gov
Forecast / Agency code HHS-NIH11
Forecast / Applicant eligibility desc Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
Forecast / Est synopsis posting date Jul 10, 2026 12:00:00 AM EDT
Forecast / Est application response date Oct 09, 2026 12:00:00 AM EDT
Forecast / Est award date Jul 01, 2027 12:00:00 AM EDT
Forecast / Est project start date Jul 01, 2027 12:00:00 AM EDT
Forecast / Fiscal year 2027
Forecast / Mod comments Updated Archive Date
Forecast / Create time stamp Sep 01, 2026 07:55:14 AM EDT
Forecast / Created date Apr 09, 2026 03:29:59 PM EDT
Forecast / Last updated date Sep 01, 2026 07:55:14 AM EDT
Forecast / Agency details / Code NIH
Forecast / Agency details / Seed HHS-NIH11
Forecast / Agency details / Agency name National Institutes of Health
Forecast / Agency details / Agency code HHS-NIH11
Forecast / Agency details / Top agency code HHS
Forecast / Applicant types 1 / Id 02
Forecast / Applicant types 1 / Description City or township governments
Forecast / Applicant types 2 / Id 01
Forecast / Applicant types 2 / Description County governments
Forecast / Applicant types 3 / Id 11
Forecast / Applicant types 3 / Description Native American tribal organizations (other than Federally recognized tribal governments)
Forecast / Applicant types 4 / Id 06
Forecast / Applicant types 4 / Description Public and State controlled institutions of higher education
Forecast / Applicant types 5 / Id 05
Forecast / Applicant types 5 / Description Independent school districts
Forecast / Applicant types 6 / Id 07
Forecast / Applicant types 6 / Description Native American tribal governments (Federally recognized)
Forecast / Applicant types 7 / Id 08
Forecast / Applicant types 7 / Description Public housing authorities/Indian housing authorities
Forecast / Applicant types 8 / Id 23
Forecast / Applicant types 8 / Description Small businesses
Forecast / Applicant types 9 / Id 13
Forecast / Applicant types 9 / Description Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Forecast / Applicant types 10 / Id 00
Forecast / Applicant types 10 / Description State governments
Forecast / Applicant types 11 / Id 04
Forecast / Applicant types 11 / Description Special district governments
Forecast / Applicant types 12 / Id 22
Forecast / Applicant types 12 / Description For profit organizations other than small businesses
Forecast / Applicant types 13 / Id 25
Forecast / Applicant types 13 / Description Others (see text field entitled "Additional Information on Eligibility" for clarification)
Forecast / Applicant types 14 / Id 12
Forecast / Applicant types 14 / Description Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Forecast / Applicant types 15 / Id 20
Forecast / Applicant types 15 / Description Private institutions of higher education
Forecast / Funding instruments 1 / Id CA
Forecast / Funding instruments 1 / Description Cooperative Agreement
Forecast / Funding activity categories 1 / Id HL
Forecast / Funding activity categories 1 / Description Health
Forecast / Posting date str 2026-04-09-00-00-00
Forecast / Archive date str 2026-08-31-00-00-00
Forecast / Est synopsis posting date str 2026-07-10-00-00-00
Forecast / Est application response date str 2026-10-09-00-00-00
Forecast / Est award date str 2027-07-01-00-00-00
Forecast / Est project start date str 2027-07-01-00-00-00
Forecast / Create time stamp str 2026-09-01-07-55-14
Synopsis attachment folders 1 / Id 81220
Synopsis attachment folders 1 / Opportunity id 361833
Synopsis attachment folders 1 / Folder type Full Announcement
Synopsis attachment folders 1 / Folder name Full Announcement
Synopsis attachment folders 1 / Zip lob size 31506
Synopsis attachment folders 1 / Created date Sep 01, 2026 07:55:13 AM EDT
Synopsis attachment folders 1 / Last updated date Sep 01, 2026 07:55:14 AM EDT
Synopsis attachment folders 1 / Synopsis attachments 1 / Id 354898
Synopsis attachment folders 1 / Synopsis attachments 1 / Opportunity id 361833
Synopsis attachment folders 1 / Synopsis attachments 1 / Mime type text/html;charset=UTF-8
Synopsis attachment folders 1 / Synopsis attachments 1 / File name RFA-AI-27-014-Full-Announcement.html
Synopsis attachment folders 1 / Synopsis attachments 1 / File description RFA-AI-27-014-Full-Announcement.html
Synopsis attachment folders 1 / Synopsis attachments 1 / File lob size 134778
Synopsis attachment folders 1 / Synopsis attachments 1 / Created date Sep 01, 2026 07:55:14 AM EDT
Synopsis attachment folders 1 / Synopsis attachments 1 / Synopsis att folder id 81220
Synopsis document urls Not specified
Syn att change comments Not specified
Cfdas 1 / Id 435276
Cfdas 1 / Opportunity id 361833
Cfdas 1 / Cfda number 93.233
Cfdas 1 / Program title National Center on Sleep Disorders Research
Cfdas 2 / Id 432623
Cfdas 2 / Opportunity id 361833
Cfdas 2 / Cfda number 93.279
Cfdas 2 / Program title Drug Use and Addiction Research Programs
Cfdas 3 / Id 435275
Cfdas 3 / Opportunity id 361833
Cfdas 3 / Cfda number 93.837
Cfdas 3 / Program title Cardiovascular Diseases Research
Cfdas 4 / Id 435278
Cfdas 4 / Opportunity id 361833
Cfdas 4 / Cfda number 93.838
Cfdas 4 / Program title Lung Diseases Research
Cfdas 5 / Id 435277
Cfdas 5 / Opportunity id 361833
Cfdas 5 / Cfda number 93.839
Cfdas 5 / Program title Blood Diseases and Resources Research
Cfdas 6 / Id 435279
Cfdas 6 / Opportunity id 361833
Cfdas 6 / Cfda number 93.840
Cfdas 6 / Program title Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
Cfdas 7 / Id 432621
Cfdas 7 / Opportunity id 361833
Cfdas 7 / Cfda number 93.846
Cfdas 7 / Program title Arthritis, Musculoskeletal and Skin Diseases Research
Cfdas 8 / Id 432620
Cfdas 8 / Opportunity id 361833
Cfdas 8 / Cfda number 93.853
Cfdas 8 / Program title Extramural Research Programs in the Neurosciences and Neurological Disorders
Cfdas 9 / Id 432624
Cfdas 9 / Opportunity id 361833
Cfdas 9 / Cfda number 93.855
Cfdas 9 / Program title Allergy and Infectious Diseases Research
Cfdas 10 / Id 432622
Cfdas 10 / Opportunity id 361833
Cfdas 10 / Cfda number 93.867
Cfdas 10 / Program title Vision Research
Opportunity pkgs 1 / Id 294097
Opportunity pkgs 1 / Topportunity id 361833
Opportunity pkgs 1 / Family id 14
Opportunity pkgs 1 / Dialect XFDL2.2
Opportunity pkgs 1 / Opportunity number RFA-AI-27-014
Opportunity pkgs 1 / Opportunity title Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed)
Opportunity pkgs 1 / Cfda number 93.855
Opportunity pkgs 1 / Opening date 2026-10-09
Opportunity pkgs 1 / Closing date 2028-10-09
Opportunity pkgs 1 / Owning agency code HHS-NIH11
Opportunity pkgs 1 / Agency details / Code NIH
Opportunity pkgs 1 / Agency details / Seed HHS-NIH11
Opportunity pkgs 1 / Agency details / Agency name National Institutes of Health
Opportunity pkgs 1 / Agency details / Agency code HHS-NIH11
Opportunity pkgs 1 / Agency details / Top agency code HHS
Opportunity pkgs 1 / Top agency details / Code HHS
Opportunity pkgs 1 / Top agency details / Seed HHS
Opportunity pkgs 1 / Top agency details / Agency name Department of Health and Human Services
Opportunity pkgs 1 / Top agency details / Agency code HHS
Opportunity pkgs 1 / Top agency details / Top agency code HHS
Opportunity pkgs 1 / Program title Allergy and Infectious Diseases Research
Opportunity pkgs 1 / Contact info eRA Service Desk
https://www.era.nih.gov/need-help
Opportunity pkgs 1 / Grace period 60
Opportunity pkgs 1 / Competition id FORMS-I
Opportunity pkgs 1 / Competition title Use for due date on or after January 25, 2025.
Opportunity pkgs 1 / Electronic required Y
Opportunity pkgs 1 / Expected application count 100
Opportunity pkgs 1 / Open to applicant type 1
Opportunity pkgs 1 / Is multi project N
Opportunity pkgs 1 / Extension pdf
Opportunity pkgs 1 / Mimetype application/pdf
Opportunity pkgs 1 / Last update Sep 01, 2026 07:55:46 AM EDT
Opportunity pkgs 1 / Workspace compatible flag Y
Opportunity pkgs 1 / Package id PKG00294097
Opportunity pkgs 1 / Opening date str 2026-10-09-00-00-00
Opportunity pkgs 1 / Closing date str 2028-10-09-00-00-00
Closed opportunity pkgs Not specified
Original due date Oct 09, 2028 12:00:00 AM EDT
Synopsis modified fields Not specified
Forecast modified fields revision; version; archiveDate; modComments
Error messages Not specified
Syn post date in past Yes
Doc type synopsis
Forecast hist count 3
Synopsis hist count 0
Assist compatible No
Assist url Not specified
Related opps Not specified
Ost POSTED

Related Documents

There are no related documents on this grant.

Packages

Agency Contact Information: National Institute of Allergy and Infectious Diseases (NIAID)
RADCHEM_U01@mail.nih.gov
Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
93.855 FORMS-I Use for due date on or after January 25, 2025. PKG00294097 2026-10-09 2028-10-09 View

Package 1

Instructions

PKG00294120-instructions.pdf

Mandatory forms

RR_SF424_5_0-V5.0.pdf
PHS398_CoverPageSupplement_5_0-V5.0.pdf
RR_OtherProjectInfo_1_4-V1.4.pdf
PerformanceSite_4_0-V4.0.pdf
RR_KeyPersonExpanded_4_0-V4.0.pdf
PHS398_ResearchPlan_5_0-V5.0.pdf
PHSHumanSubjectsAndClinicalTrialsInfo_3_0-V3.0.pdf

Optional forms

RR_Budget_3_0-V3.0.pdf
RR_SubawardBudget30_3_0-V3.0.pdf
PHS398_ModularBudget_1_2-V1.2.pdf
PHS_AssignmentRequestForm_4_0-V4.0.pdf

osnqt2026-09-15T23:23:00-05:00

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