This grant from a Health Research Department invites multidisciplinary investigators to develop novel approaches for measuring brain activity, connectivity, or genomics across the neurodevelopmental age spectrum. This grant is for the purpose of advancing understanding of brain development and aging, and predicting outcomes through improved long-term repeated measures. Research can involve healthy humans, clinical groups, or animals, focusing on longitudinal neuroanatomical or functional changes from genetic to connectomic levels. This R21 mechanism encourages high-risk, high-reward innovations, supporting ideas needing preliminary data.
Opportunity ID: 357377
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-272 |
| Funding Opportunity Title: | New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.396 — Cancer Biology Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 25, 2024 |
| Last Updated Date: | Nov 25, 2024 |
| Original Closing Date for Applications: | May 07, 2027 |
| Current Closing Date for Applications: | May 07, 2027 |
| Archive Date: | Jun 12, 2027 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Special district governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Small businesses Independent school districts For profit organizations other than small businesses State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity is to encourage multidisciplinary investigators to submit applications developing exploratory, highly novel new approaches, or innovative applications of existing approaches to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease, by improving repeated measures across longer epochs of the lifespan to better predict outcomes at later ages. . Research can include healthy human participants of any age, specific clinical groups such those with cognitive, motor, or affective regulation challenges, and/or animal research on these domains of function. The studies can focus on longitudinal neuroanatomical or functional changes at any level, including genetics/genomics, single cells, connectomics, neural population activity patterns, and others. This funding opportunity is intended to encourage technological and conceptual innovation through this high risk, high reward funding mechanism to develop highly innovative ideas that either lack preliminary data or need additional preliminary data |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-272.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357377 Full Announcement-PAR-25-272 -> PAR-25-272-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288973 | Jan 16, 2025 | May 07, 2027 | View |
Package 1
Mandatory forms
357377 RR_SF424_5_0-5.0.pdf
357377 PHS398_CoverPageSupplement_5_0-5.0.pdf
357377 RR_OtherProjectInfo_1_4-1.4.pdf
357377 PerformanceSite_4_0-4.0.pdf
357377 RR_KeyPersonExpanded_4_0-4.0.pdf
357377 PHS398_ResearchPlan_5_0-5.0.pdf
357377 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357377 RR_Budget_3_0-3.0.pdf
357377 RR_SubawardBudget30_3_0-3.0.pdf
357377 PHS398_ModularBudget_1_2-1.2.pdf
357377 PHS_AssignmentRequestForm_4_0-4.0.pdf