This grant aims to establish Omics Production Centers (OPCs) as part of a collaborative initiative to advance multi-omic technologies for health and disease research in diverse populations. These centers will work with Disease Study Sites and a Data Analysis and Coordination Center. The OPCs will leverage clinical conditions to explore multi-omics integrated with phenotypic, environmental, and social determinants of health data to identify molecular profiles. They will develop generalizable data harmonization and analysis methods, establishing best practices for optimal multi-omic application. Their primary role involves high-throughput molecular assays to produce omics data from biosamples. The ultimate goal is to validate and enhance multi-omic approaches to identify meaningful biological changes, creating a multi-dimensional dataset available to the research community.
Opportunity ID: 343393
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HG-22-009 |
| Funding Opportunity Title: | Multi-Omics for Health and Disease – ‘Omics Production Centers (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Environment Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 07, 2022 |
| Last Updated Date: | Sep 07, 2022 |
| Original Closing Date for Applications: | Nov 18, 2022 |
| Current Closing Date for Applications: | Nov 18, 2022 |
| Archive Date: | Dec 24, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $2,700,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments Native American tribal governments (Federally recognized) Small businesses County governments For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments State governments Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of this Funding Opportunity Announcement (FOA) is to establish Omics Production Center(s) (OPC(s)) that will be part of a collaborative initiative to advance the application of multi-omic technologies to study health and disease in diverse populations. Together with the Disease Study Sites (RFA-HG-22-008) and the Data Analysis and Coordination Center (RFA-HG-22-010), the Omics Production Center(s) will leverage clinical conditions where multi-omic approaches are expected to be most informative to: 1) explore the use of multi-omics, integrated with phenotypic and environmental exposure data, including social determinants of health (SDOH), to detect and assess molecular profiles associated with healthy and disease states; 2) develop generalizable data harmonization, integration, and analysis methods, as well as best practices and standards for the optimal application of multi-omics; and 3) create a multi-dimensional dataset that is available to the research community. The OPC(s) will be primarily responsible for using high high-throughput molecular assays to produce omics data from the biosamples provided by the Disease Study Sites (DSS, RFA-HG-22-008) and contributing to consortium-wide protocol development, data analysis, methods development, and the production of the multi-dimensional dataset. While this program may provide some insights into disease etiology, its primary goal is to validate and enhance generalizable multi-omic approaches to identify meaningful biological changes related to health and disease. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-HG-22-009.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 343393 Full Announcement-RFA-HG-22-009 -> RFA-HG-22-009-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00276676 | Oct 18, 2022 | Nov 18, 2022 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00277984 | Nov 04, 2022 | Nov 18, 2022 | View |
Package 1
Mandatory forms
343393 RR_SF424_5_0-5.0.pdf
343393 PHS398_CoverPageSupplement_5_0-5.0.pdf
343393 RR_OtherProjectInfo_1_4-1.4.pdf
343393 PerformanceSite_4_0-4.0.pdf
343393 RR_KeyPersonExpanded_4_0-4.0.pdf
343393 PHS398_ResearchPlan_4_0-4.0.pdf
343393 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343393 RR_Budget_3_0-3.0.pdf
343393 RR_SubawardBudget30_3_0-3.0.pdf
343393 PHS398_ModularBudget_1_2-1.2.pdf
343393 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
343393 RR_SF424_5_0-5.0.pdf
343393 PHS398_CoverPageSupplement_5_0-5.0.pdf
343393 RR_OtherProjectInfo_1_4-1.4.pdf
343393 PerformanceSite_4_0-4.0.pdf
343393 RR_KeyPersonExpanded_4_0-4.0.pdf
343393 PHS398_ResearchPlan_5_0-5.0.pdf
343393 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343393 RR_Budget_3_0-3.0.pdf
343393 RR_SubawardBudget30_3_0-3.0.pdf
343393 PHS398_ModularBudget_1_2-1.2.pdf
343393 PHS_AssignmentRequestForm_3_0-3.0.pdf
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