The Agency for Toxic Substances and Disease Registry (ATSDR) is offering a grant to conduct a multi-site study on the health implications of exposure to drinking water contaminated with PFAS. Research sites must involve communities using PFAS-contaminated water sources. The grant entails conducting historical reconstructions and water modeling to determine PFAS concentrations, assessing biomarkers, and proposing additional research questions. ATSDR aims for a comprehensive analysis to understand the human health effects of PFAS exposure. Closing date for applications is June 3, 2019.
Opportunity ID: 314434
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TS-19-002 |
| Funding Opportunity Title: | Multi-Site Study of the Health Implications of Exposure to PFAS-Contaminated Drinking Water |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 6 |
| Assistance Listings: | 93.070 — Environmental Public Health and Emergency Response |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 6 |
| Posted Date: | Apr 01, 2019 |
| Last Updated Date: | May 31, 2019 |
| Original Closing Date for Applications: | May 30, 2019 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date. |
| Current Closing Date for Applications: | Jun 03, 2019 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date. |
| Archive Date: | Jul 03, 2019 |
| Estimated Total Program Funding: | $32,500,000 |
| Award Ceiling: | $3,000,000 |
| Award Floor: | $500,000 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Native American tribal organizations (other than Federally recognized tribal governments) State governments Special district governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses Independent school districts Private institutions of higher education Native American tribal governments (Federally recognized) City or township governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Centers for Disease Control and Prevention – ERA |
| Description: | The Agency for Toxic Substances and Disease Registry (ATSDR) is soliciting research to commence a multi-site study on the human health effects of exposures to drinking water contaminated with per- and polyfluoroalkyl substances (PFAS). Proposed study sites must include communities using PFAS-contaminated private residential wells or public water systems. Exposure assessment will be based on measured PFAS serum levels as well as estimated PFAS serum levels derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time. Specifically, grant awardees will be required to conduct historical reconstruction/water modeling in order to determine the PFAS concentration.Effect biomarkers such as lipids and tests of immune and thyroid function derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time will be evaluated.ATSDR intends this research to be a two-part program consisting of (1) a mandatory core research protocol to allow ATSDR to aggregate the core data and to compare laboratory and statistical analyses across sites, and (2) each successful awardee will have the option to propose additional investigator-initiated research questions and hypotheses related to the overall goals of this NOFO. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Dan Holcomb
DWH6@cdc.gov Email:DWH6@cdc.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| The application due has been extended until June 3, 2019. | May 31, 2019 | |
| The application due has been extended until June 3, 2019. | Apr 01, 2019 | |
| The application due has been extended until June 3, 2019. | Apr 01, 2019 | |
| The application due has been extended until June 3, 2019. | Apr 01, 2019 | |
| Revision | Apr 01, 2019 | |
| Apr 01, 2019 |
DISPLAYING: Synopsis 6
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TS-19-002 |
| Funding Opportunity Title: | Multi-Site Study of the Health Implications of Exposure to PFAS-Contaminated Drinking Water |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 6 |
| Assistance Listings: | 93.070 — Environmental Public Health and Emergency Response |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 6 |
| Posted Date: | Apr 01, 2019 |
| Last Updated Date: | May 31, 2019 |
| Original Closing Date for Applications: | May 30, 2019 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date. |
| Current Closing Date for Applications: | Jun 03, 2019 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date. |
| Archive Date: | Jul 03, 2019 |
| Estimated Total Program Funding: | $32,500,000 |
| Award Ceiling: | $3,000,000 |
| Award Floor: | $500,000 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Native American tribal organizations (other than Federally recognized tribal governments) State governments Special district governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses Independent school districts Private institutions of higher education Native American tribal governments (Federally recognized) City or township governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Centers for Disease Control and Prevention – ERA |
| Description: | The Agency for Toxic Substances and Disease Registry (ATSDR) is soliciting research to commence a multi-site study on the human health effects of exposures to drinking water contaminated with per- and polyfluoroalkyl substances (PFAS). Proposed study sites must include communities using PFAS-contaminated private residential wells or public water systems. Exposure assessment will be based on measured PFAS serum levels as well as estimated PFAS serum levels derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time. Specifically, grant awardees will be required to conduct historical reconstruction/water modeling in order to determine the PFAS concentration.Effect biomarkers such as lipids and tests of immune and thyroid function derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time will be evaluated.ATSDR intends this research to be a two-part program consisting of (1) a mandatory core research protocol to allow ATSDR to aggregate the core data and to compare laboratory and statistical analyses across sites, and (2) each successful awardee will have the option to propose additional investigator-initiated research questions and hypotheses related to the overall goals of this NOFO. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Dan Holcomb
DWH6@cdc.gov Email:DWH6@cdc.gov |
DISPLAYING: Synopsis 5
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TS-19-002 |
| Funding Opportunity Title: | Multi-Site Study of the Health Implications of Exposure to PFAS-Contaminated Drinking Water |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 6 |
| Assistance Listings: | 93.070 — Environmental Public Health and Emergency Response |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 5 |
| Posted Date: | Apr 01, 2019 |
| Last Updated Date: | May 31, 2019 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Jun 03, 2019 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date. |
| Archive Date: | Jul 03, 2019 |
| Estimated Total Program Funding: | $32,500,000 |
| Award Ceiling: | $3,000,000 |
| Award Floor: | $500,000 |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Private institutions of higher education Native American tribal governments (Federally recognized) Independent school districts Public housing authorities/Indian housing authorities State governments County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” For profit organizations other than small businesses Special district governments |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Centers for Disease Control and Prevention – ERA |
| Description: | The Agency for Toxic Substances and Disease Registry (ATSDR) is soliciting research to commence a multi-site study on the human health effects of exposures to drinking water contaminated with per- and polyfluoroalkyl substances (PFAS). Proposed study sites must include communities using PFAS-contaminated private residential wells or public water systems. Exposure assessment will be based on measured PFAS serum levels as well as estimated PFAS serum levels derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time. Specifically, grant awardees will be required to conduct historical reconstruction/water modeling in order to determine the PFAS concentration.Effect biomarkers such as lipids and tests of immune and thyroid function derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time will be evaluated.ATSDR intends this research to be a two-part program consisting of (1) a mandatory core research protocol to allow ATSDR to aggregate the core data and to compare laboratory and statistical analyses across sites, and (2) each successful awardee will have the option to propose additional investigator-initiated research questions and hypotheses related to the overall goals of this NOFO. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Dan Holcomb
DWH6@cdc.gov Email:DWH6@cdc.gov |
DISPLAYING: Synopsis 4
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TS-19-002 |
| Funding Opportunity Title: | Multi-Site Study of the Health Implications of Exposure to PFAS-Contaminated Drinking Water |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 6 |
| Assistance Listings: | 93.070 — Environmental Public Health and Emergency Response |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 4 |
| Posted Date: | Apr 01, 2019 |
| Last Updated Date: | May 31, 2019 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Jun 03, 2019 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date. |
| Archive Date: | Jul 03, 2019 |
| Estimated Total Program Funding: | $32,500,000 |
| Award Ceiling: | $3,000,000 |
| Award Floor: | $500,000 |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Private institutions of higher education Native American tribal governments (Federally recognized) Independent school districts Public housing authorities/Indian housing authorities State governments County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” Special district governments |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Centers for Disease Control and Prevention – ERA |
| Description: | The Agency for Toxic Substances and Disease Registry (ATSDR) is soliciting research to commence a multi-site study on the human health effects of exposures to drinking water contaminated with per- and polyfluoroalkyl substances (PFAS). Proposed study sites must include communities using PFAS-contaminated private residential wells or public water systems. Exposure assessment will be based on measured PFAS serum levels as well as estimated PFAS serum levels derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time. Specifically, grant awardees will be required to conduct historical reconstruction/water modeling in order to determine the PFAS concentration.Effect biomarkers such as lipids and tests of immune and thyroid function derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time will be evaluated.ATSDR intends this research to be a two-part program consisting of (1) a mandatory core research protocol to allow ATSDR to aggregate the core data and to compare laboratory and statistical analyses across sites, and (2) each successful awardee will have the option to propose additional investigator-initiated research questions and hypotheses related to the overall goals of this NOFO. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Dan Holcomb
DWH6@cdc.gov Email:DWH6@cdc.gov |
DISPLAYING: Synopsis 3
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TS-19-002 |
| Funding Opportunity Title: | Multi-Site Study of the Health Implications of Exposure to PFAS-Contaminated Drinking Water |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 6 |
| Assistance Listings: | 93.070 — Environmental Public Health and Emergency Response |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 3 |
| Posted Date: | Apr 01, 2019 |
| Last Updated Date: | May 31, 2019 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Jun 03, 2019 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date. |
| Archive Date: | Jul 03, 2019 |
| Estimated Total Program Funding: | $32,500,000 |
| Award Ceiling: | $3,000,000 |
| Award Floor: | $500,000 |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Private institutions of higher education Native American tribal governments (Federally recognized) Independent school districts Public housing authorities/Indian housing authorities State governments County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” Special district governments |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Centers for Disease Control and Prevention – ERA |
| Description: | The Agency for Toxic Substances and Disease Registry (ATSDR) is soliciting research to commence a multi-site study on the human health effects of exposures to drinking water contaminated with per- and polyfluoroalkyl substances (PFAS). Proposed study sites must include communities using PFAS-contaminated private residential wells or public water systems. Exposure assessment will be based on measured PFAS serum levels as well as estimated PFAS serum levels derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time. Specifically, grant awardees will be required to conduct historical reconstruction/water modeling in order to determine the PFAS concentration.Effect biomarkers such as lipids and tests of immune and thyroid function derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time will be evaluated.ATSDR intends this research to be a two-part program consisting of (1) a mandatory core research protocol to allow ATSDR to aggregate the core data and to compare laboratory and statistical analyses across sites, and (2) each successful awardee will have the option to propose additional investigator-initiated research questions and hypotheses related to the overall goals of this NOFO. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Dan Holcomb
DWH6@cdc.gov Email:DWH6@cdc.gov |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TS-19-002 |
| Funding Opportunity Title: | Multi-Site Study of the Health Implications of Exposure to PFAS-Contaminated Drinking Water |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 6 |
| Assistance Listings: | 93.070 — Environmental Public Health and Emergency Response |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Apr 01, 2019 |
| Last Updated Date: | May 10, 2019 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | May 30, 2019 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date. |
| Archive Date: | Jun 29, 2019 |
| Estimated Total Program Funding: | $32,500,000 |
| Award Ceiling: | $3,000,000 |
| Award Floor: | $500,000 |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Private institutions of higher education Native American tribal governments (Federally recognized) Independent school districts Public housing authorities/Indian housing authorities County governments State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” Special district governments |
| Additional Information on Eligibility: |
Additional Information
| Agency Name: | Centers for Disease Control and Prevention – ERA |
| Description: | The Agency for Toxic Substances and Disease Registry (ATSDR) is soliciting research to commence a multi-site study on the human health effects of exposures to drinking water contaminated with per- and polyfluoroalkyl substances (PFAS). Proposed study sites must include communities using PFAS-contaminated private residential wells or public water systems. Exposure assessment will be based on measured PFAS serum levels as well as estimated PFAS serum levels derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time. Specifically, grant awardees will be required to conduct historical reconstruction/water modeling in order to determine the PFAS concentration. Effect biomarkers such as lipids and tests of immune and thyroid function derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time will be evaluated. ATSDR intends this research to be a two-part program consisting of (1) a mandatory core research protocol to allow ATSDR to aggregate the core data and to compare laboratory and statistical analyses across sites, and (2) each successful awardee will have the option to propose additional investigator-initiated research questions and hypotheses related to the overall goals of this NOFO. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Dan Holcomb
DWH6@cdc.gov Email:DWH6@cdc.gov |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TS-19-002 |
| Funding Opportunity Title: | Multi-Site Study of the Health Implications of Exposure to PFAS-Contaminated Drinking Water |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 6 |
| Assistance Listings: | 93.070 — Environmental Public Health and Emergency Response |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 01, 2019 |
| Last Updated Date: | Apr 01, 2019 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | May 30, 2019 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date. |
| Archive Date: | Jun 29, 2019 |
| Estimated Total Program Funding: | $32,500,000 |
| Award Ceiling: | $3,000,000 |
| Award Floor: | $500,000 |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Private institutions of higher education Native American tribal governments (Federally recognized) Independent school districts Public housing authorities/Indian housing authorities State governments County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” Special district governments |
| Additional Information on Eligibility: |
Additional Information
| Agency Name: | Centers for Disease Control and Prevention – ERA |
| Description: | The Agency for Toxic Substances and Disease Registry (ATSDR) is soliciting research to commence a multi-site study on the human health effects of exposures to drinking water contaminated with per- and polyfluoroalkyl substances (PFAS). Proposed study sites must include communities using PFAS-contaminated private residential wells or public water systems. Exposure assessment will be based on measured PFAS serum levels as well as estimated PFAS serum levels derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time. Specifically, grant awardees will be required to conduct historical reconstruction/water modeling in order to determine the PFAS concentration. Effect biomarkers such as lipids and tests of immune and thyroid function derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time will be evaluated. ATSDR intends this research to be a two-part program consisting of (1) a mandatory core research protocol to allow ATSDR to aggregate the core data and to compare laboratory and statistical analyses across sites, and (2) each successful awardee will have the option to propose additional investigator-initiated research questions and hypotheses related to the overall goals of this NOFO. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Dan Holcomb
DWH6@cdc.gov Email:DWH6@cdc.gov |
Related Documents
Folder 314434 Full Announcement-FULL_ANNOUNCEMENT -> RFA-TS-19-002.pdf
Folder 314434 Revised Full Announcement-REVISED_FULL_ANNOUNCEMENT -> RFA-TS-19-002 Revised 05 31 19.pdf
Packages
| Agency Contact Information: | Dan Holcomb DWH6@cdc.gov Email: DWH6@cdc.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.070 | RFA-TS-19-002 | Multi-Site Study of the Health Implications of Exposure to PFAS-Contaminated Drinking Water | PKG00249584 | Mar 28, 2019 | Jun 03, 2019 | View |
Package 1
Mandatory forms
314434 RR_SF424_2_0-2.0.pdf
314434 RR_Budget_1_4-1.4.pdf
314434 PHS398_ResearchPlan_4_0-4.0.pdf
314434 PHS398_CoverPageSupplement_4_0-4.0.pdf
314434 RR_OtherProjectInfo_1_4-1.4.pdf
314434 PerformanceSite_2_0-2.0.pdf
314434 RR_KeyPersonExpanded_2_0-2.0.pdf
Optional forms
314434 RR_SubawardBudget30_1_4-1.4.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
