The BRAIN Initiative is offering this grant to facilitate the translation of cutting-edge recording and modulation technologies specifically designed for the human central nervous system (CNS). The core purpose of this funding is to enable the development of novel tools that can effectively treat and/or diagnose a wide range of CNS diseases and disorders, while also deepening our fundamental understanding of the human brain. This grant supports projects progressing from their initial proof-of-concept phase, aiming for readiness for first-in-human (FIH) studies. Technologies can encompass various signal modalities such as electrical, optical, magnetic, or acoustic, or combinations thereof. The initiative strongly encourages diverse, team-based applications that integrate appropriate expertise to drive these critical neurotechnology advancements.
Opportunity ID: 353055
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-NS-24-031 |
| Funding Opportunity Title: | BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.173 — Research Related to Deafness and Communication Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 19, 2024 |
| Last Updated Date: | Mar 19, 2024 |
| Original Closing Date for Applications: | Jan 28, 2027 |
| Current Closing Date for Applications: | Jan 28, 2027 |
| Archive Date: | Mar 05, 2027 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $750,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Special district governments State governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Private institutions of higher education City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Awarded activities will facilitate the translation of novel recording and modulation technologies that can be used to treat and/or diagnose central nervous system (CNS) diseases and disorders and to better understand the human CNS, from proof of concept up to the stage of readiness for first in human (FIH) studies. Technologies may incorporate any signal modality (e.g., electrical, optical, magnetic, acoustic) or a combination thereof. Diverse team-based applications that integrate appropriate domains of expertise are encouraged. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-031.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00286225 | May 03, 2024 | Jan 24, 2025 | View | |
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289130 | Nov 26, 2024 | Jan 28, 2027 | View |
Package 1
Mandatory forms
353055 RR_SF424_5_0-5.0.pdf
353055 PHS398_CoverPageSupplement_5_0-5.0.pdf
353055 RR_OtherProjectInfo_1_4-1.4.pdf
353055 PerformanceSite_4_0-4.0.pdf
353055 RR_KeyPersonExpanded_4_0-4.0.pdf
353055 RR_Budget_3_0-3.0.pdf
353055 PHS398_ResearchPlan_5_0-5.0.pdf
353055 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
353055 RR_SubawardBudget30_3_0-3.0.pdf
353055 PHS_AssignmentRequestForm_4_0-4.0.pdf
Package 2
Mandatory forms
353055 RR_SF424_5_0-5.0.pdf
353055 PHS398_CoverPageSupplement_5_0-5.0.pdf
353055 RR_OtherProjectInfo_1_4-1.4.pdf
353055 PerformanceSite_4_0-4.0.pdf
353055 RR_KeyPersonExpanded_4_0-4.0.pdf
353055 RR_Budget_3_0-3.0.pdf
353055 PHS398_ResearchPlan_5_0-5.0.pdf
353055 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
353055 RR_SubawardBudget30_3_0-3.0.pdf
353055 PHS_AssignmentRequestForm_3_0-3.0.pdf
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