The Centers for Disease Control/Agency for Toxic Substances and Disease Registry (CDC/ATSDR) is offering this grant to support investigator-initiated research aimed at deepening the understanding of potential risk factors for Amyotrophic Lateral Sclerosis (ALS). This initiative aligns with the National ALS Registry’s mission to better understand ALS prevalence, incidence, and contributing factors, particularly environmental ones. The grant is for identifying and evaluating diverse risk factors, with a preferred focus on those linked to military service, contact sports, traumatic brain injury, neuroinflammation, environmental exposures, and infectious agents. Two funding options are available: Option A supports rigorous evaluation of well-substantiated research, while Option B targets novel, exploratory investigations, even with limited preliminary data. Applicants may choose to utilize National ALS Registry data, though it’s not mandatory.
Opportunity ID: 347167
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TS-24-010 |
| Funding Opportunity Title: | Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 8 |
| Assistance Listings: | 93.061 — Innovations in Applied Public Health Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 01, 2023 |
| Last Updated Date: | Aug 01, 2023 |
| Original Closing Date for Applications: | Dec 19, 2023 Electronically submitted applications must be submitted no later than 11:59 pm ET on the listed application due date. |
| Current Closing Date for Applications: | Dec 19, 2023 Electronically submitted applications must be submitted no later than 11:59 pm ET on the listed application due date. |
| Archive Date: | Jan 18, 2024 |
| Estimated Total Program Funding: | $7,500,000 |
| Award Ceiling: | $500,000 |
| Award Floor: | $0 |
Eligibility
| Eligible Applicants: | County governments City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” State governments Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Special district governments Native American tribal governments (Federally recognized) Independent school districts Private institutions of higher education For profit organizations other than small businesses |
| Additional Information on Eligibility: | See Section III. Eligibility Information. |
Additional Information
| Agency Name: | Centers for Disease Control and Prevention – ERA |
| Description: | The Centers for Disease Control/Agency for Toxic Substances and Disease Registry (CDC/ATSDR) is seeking investigator-initiated research that will further the understanding of potential risk factors for Amyotrophic Lateral Sclerosis (ALS), while supporting the National ALS Registry’s mission. The National ALS Registry’s goals are to estimate the number of new ALS cases each year, estimate the number of people who have ALS at a specific point in time, better understand who gets ALS, and identify what contributing factors, including environmental, may affect ALS. CDC/ATSDR is seeking investigator-initiated research that will identify and evaluate risk factors contributing to ALS, with preferred focus in this Notice of Funding Opportunity on factors related to military service, contact sports, traumatic brain injury, neuroinflammation, environmental exposures, and infectious agents. Research proposals on preferred topics can be funded under one of two funding options, Funding Option A or Funding Option B.Funding Option A is intended to support ALS risk factor research investigations that have an existing, well substantiated evidence base and would benefit from strengthened rigorous evaluation. Funding Option B is intended to support novel ALS risk factor research investigations that may or may not have an existing evidence base foundation base, may be supported by limited and insufficient preliminary research, and are exploratory and developmental in nature.For Option A and B applicants may elect to use data from the National ALS Registry. Note, this is not compulsory and will not preclude the applicant from consideration. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Candis M. Hunter, PhD, MSPH, REHS/RS
ncipc_erpo@cdc.gov Email:ncipc_erpo@cdc.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 347167 Full Announcement-Full Announcement -> RFA-TS-24-010.pdf
Folder 347167 Other Supporting Documents-Other Supporting Documents -> RFA-TS-24-010 QA FINAL.pdf
Packages
| Agency Contact Information: | Candis M. Hunter, PhD, MSPH, REHS/RS ncipc_erpo@cdc.gov Email: ncipc_erpo@cdc.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.061 | RFA-TS-24-010 | Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS) | PKG00282755 | Aug 01, 2023 | Dec 19, 2023 | View |
Package 1
Mandatory forms
347167 RR_SF424_5_0-5.0.pdf
347167 PHS398_CoverPageSupplement_5_0-5.0.pdf
347167 PHS398_ResearchPlan_5_0-5.0.pdf
347167 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
347167 PerformanceSite_4_0-4.0.pdf
347167 RR_Budget_3_0-3.0.pdf
347167 RR_OtherProjectInfo_1_4-1.4.pdf
347167 RR_KeyPersonExpanded_4_0-4.0.pdf
Optional forms
347167 PHS_AssignmentRequestForm_3_0-3.0.pdf
347167 RR_SubawardBudget30_3_0-3.0.pdf
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