This grant, from the Dental, Oral, and Craniofacial Research Initiative, aims to advance understanding in these vital health fields. The core purpose of this funding is to support rigorous validation of Organ-on-a-Chip (OoC) technologies. This grant is for establishing OoC models as reliable tools for sophisticated disease modeling, enabling deeper insight into complex dental, oral, and craniofacial conditions. It also prioritizes pre-clinical efficacy studies utilizing these validated OoC systems. By funding this research, the department seeks to accelerate the development and evaluation of novel therapies, leading to more effective treatments and improved patient outcomes in these specialized areas.
Opportunity ID: 356375
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DE-25-001 |
| Funding Opportunity Title: | Organs-on-a-Chip in Dental, Oral, and Craniofacial Research (DOC-OoCs) (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 09, 2024 |
| Last Updated Date: | Sep 09, 2024 |
| Original Closing Date for Applications: | Nov 19, 2024 |
| Current Closing Date for Applications: | Nov 19, 2024 |
| Archive Date: | Dec 25, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments State governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses Public housing authorities/Indian housing authorities Independent school districts County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | To support research project for validation of organ-on-a-chip (OoC) toward disease modelling and pre-clinical efficacy studies in dental, oral, and craniofacial (DOC) research. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DE-25-001.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 356375 Full Announcement-RFA-DE-25-001 -> RFA-DE-25-001-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00287877 | Oct 19, 2024 | Nov 19, 2024 | View |
Package 1
Mandatory forms
356375 RR_SF424_5_0-5.0.pdf
356375 PHS398_CoverPageSupplement_5_0-5.0.pdf
356375 RR_OtherProjectInfo_1_4-1.4.pdf
356375 PerformanceSite_4_0-4.0.pdf
356375 RR_KeyPersonExpanded_4_0-4.0.pdf
356375 PHS398_ResearchPlan_5_0-5.0.pdf
356375 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
356375 RR_Budget_3_0-3.0.pdf
356375 RR_SubawardBudget30_3_0-3.0.pdf
356375 PHS398_ModularBudget_1_2-1.2.pdf
356375 PHS_AssignmentRequestForm_3_0-3.0.pdf
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