The Department of Defense (DoD) is offering this Breast Cancer Breakthrough Award to support promising research with the potential to make significant advancements and accelerate progress towards ending breast cancer. This grant is for impactful projects, ranging from innovative, high-risk/high-reward early-stage ideas (Funding Level 1) to research with preliminary data aiming for laboratory-to-clinic translation (Funding Level 2). Applicants must propose a detailed implementation plan with clear milestones. The award also encourages meaningful collaborations through a Partnering Principal Investigator option, allowing two PIs to receive separate awards for a combined effort, leveraging diverse expertise to better address research questions.
Opportunity ID: 240675
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-13-BCRP-BREAKTHROUGH2 |
| Funding Opportunity Title: | DoD Breast Cancer Breakthrough Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 20 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Aug 23, 2013 |
| Last Updated Date: | Jan 06, 2014 |
| Original Closing Date for Applications: | Jan 15, 2014 |
| Current Closing Date for Applications: | Jan 15, 2014 |
| Archive Date: | Feb 14, 2014 |
| Estimated Total Program Funding: | $13,100,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | The intent of the BCRP Breakthrough Award is to support promising research that has the potential to lead to or make breakthroughs in breast cancer. The critical components of this award mechanism are: Impact: Research supported by the Breakthrough Award will have the potential for a major impact and accelerate progress toward ending breast cancer. The impact may be near-term or long-term, but must be significant and move beyond an incremental advancement. Applications must articulate the pathway to making an impact for breast cancer patients, even if clinical impact is not an immediate outcome. Research Scope: Research proposed under this award mechanism may be at different stages of idea and research development. Two different funding levels, based on the scope of the research, are available for this solicitation of the Breakthrough Award. It is the responsibility of the Principal Investigator (PI) to select the funding level that is most appropriate for the research proposed. The following are general descriptions, although not all-inclusive, of the scope of research projects that would be appropriate to propose under each funding level: Funding Level 1: Innovative, high-risk/high-reward research that is in the earliest stages of idea development. Research with potential to yield new avenues of investigation. Proof of concept. No preliminary data required. Funding Level 2: Research that is already supported by preliminary data and has potential to make significant advancements toward translation from the laboratory to the clinic. Demonstration of efficacy in in vivo models or clinical research studies, as applicable. Implementation Plan: Applications must be supported by a detailed plan that identifies critical milestones and outlines the knowledge, resources, and technical innovations that will be utilized to achieve the milestones. A robust statistical plan and statistical expertise should be included where applicable. Partnering PI Option: The Breakthrough Award encourages applications that include meaningful and productive collaborations between investigators. The Partnering PI Option is structured to accommodate two PIs, each of whom will receive a separate award. One partner is identified as the Initiating PI, and the other partner is identified as the Partnering PI. The Initiating and Partnering PIs have different submission requirements; however, both PIs should contribute to the preparation of a single application. The collaborative partners may have expertise in similar or disparate scientific disciplines, but each partner is expected to bring different strengths to the application. New collaborations are encouraged, but not required. It is the responsibility of the collaborating investigators to describe how their combined expertise in the collaboration will better address the research question and explain why the work should be performed together rather than through separate efforts. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
CDMRP Help Desk
Phone: 301-682-5507 Email: help@cdmrp.org Email:help@cdmrp.org |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| This modification changes the Peer Review Criteria, page 16, by removing Implementation Plan as a scored criteron of the Program Announcement. | Jan 06, 2014 | |
| Jan 06, 2014 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-13-BCRP-BREAKTHROUGH2 |
| Funding Opportunity Title: | DoD Breast Cancer Breakthrough Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 20 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Aug 23, 2013 |
| Last Updated Date: | Jan 06, 2014 |
| Original Closing Date for Applications: | Jan 15, 2014 |
| Current Closing Date for Applications: | Jan 15, 2014 |
| Archive Date: | Feb 14, 2014 |
| Estimated Total Program Funding: | $13,100,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | The intent of the BCRP Breakthrough Award is to support promising research that has the potential to lead to or make breakthroughs in breast cancer. The critical components of this award mechanism are: Impact: Research supported by the Breakthrough Award will have the potential for a major impact and accelerate progress toward ending breast cancer. The impact may be near-term or long-term, but must be significant and move beyond an incremental advancement. Applications must articulate the pathway to making an impact for breast cancer patients, even if clinical impact is not an immediate outcome. Research Scope: Research proposed under this award mechanism may be at different stages of idea and research development. Two different funding levels, based on the scope of the research, are available for this solicitation of the Breakthrough Award. It is the responsibility of the Principal Investigator (PI) to select the funding level that is most appropriate for the research proposed. The following are general descriptions, although not all-inclusive, of the scope of research projects that would be appropriate to propose under each funding level: Funding Level 1: Innovative, high-risk/high-reward research that is in the earliest stages of idea development. Research with potential to yield new avenues of investigation. Proof of concept. No preliminary data required. Funding Level 2: Research that is already supported by preliminary data and has potential to make significant advancements toward translation from the laboratory to the clinic. Demonstration of efficacy in in vivo models or clinical research studies, as applicable. Implementation Plan: Applications must be supported by a detailed plan that identifies critical milestones and outlines the knowledge, resources, and technical innovations that will be utilized to achieve the milestones. A robust statistical plan and statistical expertise should be included where applicable. Partnering PI Option: The Breakthrough Award encourages applications that include meaningful and productive collaborations between investigators. The Partnering PI Option is structured to accommodate two PIs, each of whom will receive a separate award. One partner is identified as the Initiating PI, and the other partner is identified as the Partnering PI. The Initiating and Partnering PIs have different submission requirements; however, both PIs should contribute to the preparation of a single application. The collaborative partners may have expertise in similar or disparate scientific disciplines, but each partner is expected to bring different strengths to the application. New collaborations are encouraged, but not required. It is the responsibility of the collaborating investigators to describe how their combined expertise in the collaboration will better address the research question and explain why the work should be performed together rather than through separate efforts. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
CDMRP Help Desk
Phone: 301-682-5507 Email: help@cdmrp.org Email:help@cdmrp.org |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-13-BCRP-BREAKTHROUGH2 |
| Funding Opportunity Title: | DoD Breast Cancer Breakthrough Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 20 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 06, 2014 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Jan 15, 2014 |
| Archive Date: | Feb 14, 2014 |
| Estimated Total Program Funding: | $13,100,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | The intent of the BCRP Breakthrough Award is to support promising research that has the potential to lead to or make breakthroughs in breast cancer. The critical components of this award mechanism are: Impact: Research supported by the Breakthrough Award will have the potential for a major impact and accelerate progress toward ending breast cancer. The impact may be near-term or long-term, but must be significant and move beyond an incremental advancement. Applications must articulate the pathway to making an impact for breast cancer patients, even if clinical impact is not an immediate outcome. Research Scope: Research proposed under this award mechanism may be at different stages of idea and research development. Two different funding levels, based on the scope of the research, are available for this solicitation of the Breakthrough Award. It is the responsibility of the Principal Investigator (PI) to select the funding level that is most appropriate for the research proposed. The following are general descriptions, although not all-inclusive, of the scope of research projects that would be appropriate to propose under each funding level: Funding Level 1: Innovative, high-risk/high-reward research that is in the earliest stages of idea development. Research with potential to yield new avenues of investigation. Proof of concept. No preliminary data required. Funding Level 2: Research that is already supported by preliminary data and has potential to make significant advancements toward translation from the laboratory to the clinic. Demonstration of efficacy in in vivo models or clinical research studies, as applicable. Implementation Plan: Applications must be supported by a detailed plan that identifies critical milestones and outlines the knowledge, resources, and technical innovations that will be utilized to achieve the milestones. A robust statistical plan and statistical expertise should be included where applicable. Partnering PI Option: The Breakthrough Award encourages applications that include meaningful and productive collaborations between investigators. The Partnering PI Option is structured to accommodate two PIs, each of whom will receive a separate award. One partner is identified as the Initiating PI, and the other partner is identified as the Partnering PI. The Initiating and Partnering PIs have different submission requirements; however, both PIs should contribute to the preparation of a single application. The collaborative partners may have expertise in similar or disparate scientific disciplines, but each partner is expected to bring different strengths to the application. New collaborations are encouraged, but not required. It is the responsibility of the collaborating investigators to describe how their combined expertise in the collaboration will better address the research question and explain why the work should be performed together rather than through separate efforts. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
CDMRP Help Desk
Phone: 301-682-5507 Email: help@cdmrp.org Email:help@cdmrp.org |
Related Documents
Folder 240675 Full Announcement-1 -> breakthrough award_2 preapplication narrative form.pdf
Folder 240675 Full Announcement-1 -> fy13 bcrp breakthrough2 v2 pa_gg.pdf
Packages
| Agency Contact Information: | CDMRP Help Desk Phone: 301-682-5507 Email: help@cdmrp.org Email: help@cdmrp.org |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 12.420 | PKG00183872 | Aug 23, 2013 | Jan 15, 2014 | View |
Package 1
Mandatory forms
240675 RR_SF424_1_2-1.2.pdf
240675 PerformanceSite_1_4-1.4.pdf
240675 RR_Budget-1.1.pdf
Optional forms
240675 RR_SubawardBudget30-1.2.pdf
240675 RR_KeyPersonExpanded_1_2-1.2.pdf
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