The Department of Defense (DoD) is offering the Prostate Cancer Population-Based Research Award to support high-impact, population-based approaches in prostate cancer research. This grant aims to generate unique information and tools through systematic studies of defined patient populations, contributing significantly to eliminating death and suffering from prostate cancer. Applicants must propose a robust statistical plan, address the FY11 PCRP overarching challenges, or justify their project’s critical need. Eligible studies include retrospective, prospective, case control, or cohort designs, potentially using biospecimens and data from established databases with sufficient sample sizes. Research topics include biomarkers, genomics, health disparity, and risk prediction. Clinical trials are excluded; however, correlative studies with existing trial populations are permitted.
Opportunity ID: 89233
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-11-PCRP-PBRA |
| Funding Opportunity Title: | DoD FY11 Prostate Cancer Population-Based Research Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 3 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 21, 2011 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jun 08, 2011 |
| Current Closing Date for Applications: | Jun 08, 2011 |
| Archive Date: | Jul 08, 2011 |
| Estimated Total Program Funding: | $2,900,000 |
| Award Ceiling: | $0 |
| Award Floor: | $0 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | The PCRP Population-Based Research Award mechanism was first offered as the Population-Based Idea Development Award in FY09. Since then, 51 applications have been received, and 3 have been recommended for funding. The Population-Based Research Award mechanism supports high-impact, population-based approaches to prostate cancer research. Applications should clearly demonstrate the potential of the study to contribute significantly to the elimination of death and suffering from prostate cancer. The overall goal of this award is to generate unique information and/or tools that can only be achieved from the perspective of systematic studies of a defined patient population. A robust statistical plan is required and should be supported with requisite statistical expertise in the study team. All applications for the Population-Based Research Award are highly recommended to address one of the FY11 PCRP overarching challenges. The PCRP seeks to fund projects from the wide spectrum of basic to clinical research; however, if the proposed project does not address one of the overarching challenges, the application should provide a description to justify how the project will nevertheless address a critical need in the field of prostate cancer research and/or patient care. Applications may propose retrospective, prospective, case control, cohort, or other population-based study designs (including the use of biospecimens and data from established retrospective databases), provided the proposed sample is of sufficient size to demonstrate statistical significance. The study should address a well developed hypothesis that is conceptually sound and specific for prostate cancer. The statistical expertise of the study team should be clearly described and evident in the study plan. Applicants are expected to provide documentation demonstrating access to, and ability to recruit, the appropriate population(s) or patient samples in numbers sufficient to achieve statistical significance. Research proposed under the Population-Based Research Award may include the following topic areas: � Biomarkers � Predictors of response to therapy � Disease aggressiveness � Epidemiology/Public Health � Genomics (germline or somatic) � Health disparity � Molecular genetics � Risk prediction Research involving human subject use is permitted under this funding opportunity, but is restricted to studies without clinical trials; however, correlative studies, including studies with populations from existing clinical trials, are allowed. A clinical trial is defined as a prospective accrual of human subjects where an intervention (e.g., device, drug, biologic, surgical procedure, rehabilitative modality, behavioral intervention or other) is tested on a human subject for a measurable outcome with respect to exploratory information, safety, effectiveness and/or efficacy. This outcome represents a direct effect on the human subject of that intervention or interaction. For more information on clinical research, a Human Subject Resource Document is provided at https://cdmrp.org/Program_Announcements_and_Forms/. Principal Investigators (PIs) seeking funding for a clinical trial should consider submitting an application for the FY11 PCRP Clinical Trial Award. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
301-682-5507
Email:help@cdmrp.org |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 89233 Full Announcement-1 -> pcrp_fy11_pbra_ pa_gg.pdf
Packages
| Agency Contact Information: | 301-682-5507 Email: help@cdmrp.org |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 12.420 | PKG00049550 | Apr 21, 2011 | Jun 08, 2011 | View |
Package 1
Mandatory forms
89233 RR_SF424_1_2-1.2.pdf
89233 PerformanceSite_1_4-1.4.pdf
89233 RR_Budget-1.1.pdf
89233 RR_KeyPersonExpanded_1_2-1.2.pdf
Optional forms
89233 RR_SubawardBudget30-1.2.pdf
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