The Department of Defense (DoD) Tuberous Sclerosis Complex Research Program (TSCRP) offers this grant to encourage innovative research aiming to understand TSC pathogenesis and improve patient lives. This grant supports projects addressing key focus areas such as genetic modifiers, preclinical models, biomarkers, adult manifestations, mTOR inhibitor effects, and novel diagnostic/treatment strategies for TSC/LAM. Specifically, the Exploration – Hypothesis Development Award fosters initial exploration of innovative, high-risk, high-gain concepts. It provides investigators the opportunity to pursue serendipitous observations, generating scientific rationale for new hypotheses. Preliminary or published data is encouraged, but not required.
Opportunity ID: 233119
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-13-TSCRP-EHDA |
| Funding Opportunity Title: | DoD Tuberous Sclerosis Complex Exploration Hypothesis Development Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 4 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 03, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jul 11, 2013 |
| Current Closing Date for Applications: | Jul 11, 2013 |
| Archive Date: | Aug 10, 2013 |
| Estimated Total Program Funding: | $640,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | The mission of the TSCRP is to encourage innovative research aimed at understanding the pathogenesis and manifestations of TSC to improve the lives of individuals with TSC. Within this context, the FY13 TSCRP encourages applications that address one or more of these vital program Focus Areas: Genetic, epigenetic, and non-genetic modifiers of TSC. Preclinical models and therapeutic strategies (e.g., cytotoxic agents, combination therapies). Biomarkers for early detection, prognosis, and prediction of treatment outcomes (such as serum markers, imaging, electrophysiology, prenatal testing, and pharmacogenetics). Impact of TSC manifestations in adults (e.g., care management, age-specific pathogenesis, epidemiology, renal, reproductive issues, and lymphangioleiomyomatosis [LAM]). Long-term benefits and effects of mTOR inhibitors or other agents. Novel strategies for diagnosis, treatment, and prevention of TSC manifestations including those geared toward early identification and intervention. Cellular and molecular mechanisms of TSC and LAM pathogenesis. Causes and treatment of epilepsy in TSC. Causes and treatment of TSC-associated neurocognitive disorders including cognitive impairment, and psychiatric, behavioral, and sleep disorders. The Exploration Hypothesis Development Award supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in the TSC research field. The proposed research project should provide initial principles of an innovative question/concept, and results of studies conducted through this award should provide the scientific rationale upon which a new hypothesis may be developed. This award is designed to provide investigators with the opportunity to pursue serendipitous observations. The presentation of preliminary or published data is encouraged, but not required. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
CDMRP Help Desk
301-682-5507 help@cdmrp.org Email:help@cdmrp.org |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 233119 Full Announcement-1 -> tscrp_fy13 ehda pa_gg.pdf
Packages
| Agency Contact Information: | CDMRP Help Desk 301-682-5507 help@cdmrp.org Email: help@cdmrp.org |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 12.420 | PKG00176396 | May 03, 2013 | Jul 11, 2013 | View |
Package 1
Mandatory forms
233119 RR_SF424_1_2-1.2.pdf
233119 PerformanceSite_1_4-1.4.pdf
233119 RR_Budget-1.1.pdf
233119 RR_KeyPersonExpanded_1_2-1.2.pdf
Optional forms
233119 RR_SubawardBudget30-1.2.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
