This grant from the Department of Health and Human Services is offering funding for researchers to establish the APOL1 Long-term Kidney Transplantation Outcomes Research Network (APOLLO) Scientific Data Research Center (SDRC). The research will focus on studying the impact of APOL1 genetic variants in US kidney transplant recipients from African-American donors, as well as tracking outcomes in African-American kidney donors. The primary objectives include monitoring changes in kidney function, rates of acute rejection, graft failure, and dialysis return in recipients, along with assessing the health status of donors. Applications are accepted until Feb 24, 2017.
Opportunity ID: 290139
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-16-024 |
| Funding Opportunity Title: | APOL1 Long-term Kidney Transplantation Outcomes Network Scientific and Data Research Center (APOLLO SDRC) (Collaborative U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 16, 2016 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Feb 24, 2017 |
| Current Closing Date for Applications: | Feb 24, 2017 |
| Archive Date: | Mar 27, 2017 |
| Estimated Total Program Funding: | $750,000 |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments Private institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Independent school districts State governments For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites cooperative agreement applications to establish a multi-disciplinary group of investigators to be known as the APOL1 Long-term Kidney Transplantation Outcomes Research Network (APOLLO) Scientific Data Research Center (SDRC), and runs in parallel with a separate FOA that invites applications for the APOLLO Clinical Centers (CCs) (RFA-DK-16-025). The APOLLO Network consortium will design and conduct studies of a comprehensive, prospective longitudinal cohort to determine the impact of APOL1 genetic variants as susceptibility factors in US kidney transplant recipients who received kidneys from African-American donors. In addition, the consortium will follow the course of African-American kidney donors. Primary outcomes are the rate of change of kidney function in recipients, and rates of acute rejection of the kidney transplant, graft failure, and return to maintenance dialysis rates in the recipients. Outcomes in donors, including vital and renal functional status, will be assessed to the greatest extent possible. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-16-024.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00229286 | Jan 24, 2017 | Feb 24, 2017 | View |
Package 1
Mandatory forms
290139 RR_SF424_2_0-2.0.pdf
290139 PHS398_CoverPageSupplement_3_0-3.0.pdf
290139 RR_OtherProjectInfo_1_3-1.3.pdf
290139 PerformanceSite_2_0-2.0.pdf
290139 RR_KeyPersonExpanded_2_0-2.0.pdf
290139 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
290139 RR_Budget_1_3-1.3.pdf
290139 RR_SubawardBudget30_1_3-1.3.pdf
290139 PHS398_ModularBudget_1_2-1.2.pdf
290139 PHS_Inclusion_Enrollment_Report-1.0.pdf
290139 PHS_AssignmentRequestForm-1.0.pdf
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