Department of Health and Human Services Grant for Advancing Pancreatic Islet Imaging Reagents in Diabetes Research

This department is offering the DP3 grant to institutions/organizations to screen existing neuroimaging agents for enhancing pancreatic islet beta cell studies in diabetes research. The purpose is to overcome barriers in monitoring beta cell mass, unique to human pancreatic islets, by utilizing approved imaging agents for human brain studies. By leveraging human-specific neurotransmitter systems and clinical imaging facilities, this grant aims to advance the understanding of diabetes progression and individualized patient care. Applicants must submit by Feb 20, 2014.

Opportunity ID: 242577

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	RFA-DK-13-024
Funding Opportunity Title::	Harvesting the Neuroimaging Cornucopia for Pancreatic Islet Imaging Reagents for Diabetes Research (DP3)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Food and Nutrition
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.286 — Discovery and Applied Research for Technological Innovations to Improve Human Health
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Sep 13, 2013
Last Updated Date::
Original Closing Date for Applications::	Feb 20, 2014
Current Closing Date for Applications::	Feb 20, 2014
Archive Date::	Mar 23, 2014
Estimated Total Program Funding::	$ 1,000,000
Award Ceiling::	$300,000
Award Floor::	$

Eligibility

Eligible Applicants::

Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	This Funding Opportunity Announcement (FOA) encourage DP3 applications from institutions/organizations to allow researchers with access to major clinical nuclear molecular imaging facilities to screen their libraries of existing positron emission tomography (PET) or single photon emission computed tomography (SPECT) neuroimaging agents that are already approved for use in human subjects research in order to find tools to enhance in vivo study of the beta cells of the human pancreatic islet. Diabetes ensues with the loss or dysfunction of beta cells and the inability to monitor their mass is an enormous barrier to understanding the natural history of human diabetes or the course of disease in an individual patient. Because human pancreatic islet beta cells are distinct from those of rodent models of diabetes and yet have many of the neurotransmitter systems found in the human brain, screening of existing human neuroimaging agents directly in human subjects and human tissues may be a cost-efficient way to identify promising beta cell imaging agents.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID:	FORMS-C
Competition Title:	Forms-C
Opportunity Package ID:	PKG00185171
Opening Date:	Jan 20, 2014
Closing Date:	Feb 20, 2014
Agency Contact Information::	eRA Commons Help Desk
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0]
optional_forms	PHS 398 Cumulative Inclusion Enrollment Report [V1.0] Planned Enrollment Report [V1.0]