This grant aims to support research into the mechanisms of rejuvenation and accelerated aging in heterochronic blood exchange (HBE) experiments. Researchers will investigate the factors and cell types involved in transferring phenotypes between young and old animals, with a focus on identifying molecular signatures of rejuvenation or accelerated aging. The grant, offered by the Department of Health and Human Services, encourages studies to shed light on the processes underlying these phenomena. Closing date for applications is June 17, 2020.
Opportunity ID: 323138
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-21-002 |
| Funding Opportunity Title: | Mechanisms of Rejuvenation and Age-Acceleration in Heterochronic Blood Exchange (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 17, 2019 |
| Last Updated Date: | Dec 17, 2019 |
| Original Closing Date for Applications: | Jun 17, 2020 |
| Current Closing Date for Applications: | Jun 17, 2020 |
| Archive Date: | Jul 23, 2020 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $300,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Independent school districts Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Private institutions of higher education Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA will support research on aspects of rejuvenation and accelerated aging observed specifically in heterochronic blood exchange (HBE) experiments. The objectives are to identify the multiple factors involved, the multiple cell types involved and the mechanisms underlying rejuvenation or accelerated aging that is observed in the transfer of phenotypes between young and old laboratory animals. It is also anticipated that molecular signatures of rejuvenation or accelerated aging will be obtained from research supported under this FOA. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-21-002.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or before May 24, 2020 | PKG00257192 | May 17, 2020 | May 24, 2020 | View | |
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00259158 | May 17, 2020 | Jun 17, 2020 | View |
Package 1
Mandatory forms
323138 RR_SF424_2_0-2.0.pdf
323138 PHS398_CoverPageSupplement_4_0-4.0.pdf
323138 RR_OtherProjectInfo_1_4-1.4.pdf
323138 PerformanceSite_2_0-2.0.pdf
323138 RR_KeyPersonExpanded_2_0-2.0.pdf
323138 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
323138 RR_Budget_1_4-1.4.pdf
323138 RR_SubawardBudget30_1_4-1.4.pdf
323138 PHS398_ModularBudget_1_2-1.2.pdf
323138 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
323138 RR_SF424_2_0-2.0.pdf
323138 PHS398_CoverPageSupplement_5_0-5.0.pdf
323138 RR_OtherProjectInfo_1_4-1.4.pdf
323138 PerformanceSite_2_0-2.0.pdf
323138 RR_KeyPersonExpanded_2_0-2.0.pdf
323138 PHS398_ResearchPlan_4_0-4.0.pdf
323138 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
323138 RR_Budget_1_4-1.4.pdf
323138 RR_SubawardBudget30_1_4-1.4.pdf
323138 PHS398_ModularBudget_1_2-1.2.pdf
323138 PHS_AssignmentRequestForm_3_0-3.0.pdf
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