The Department of the Navy, Bureau of Medicine and Surgery (BUMED) is offering this grant to establish the Austere Environments Consortium for Enhanced Sepsis Outcomes (ACESO). This grant aims to significantly improve the prevention, early recognition, diagnosis, and treatment of severe sepsis across all causes in austere or resource-limited settings. The ACESO consortium, comprising experts in infectious disease, critical care, and global health, will conduct research focusing on rapidly translatable knowledge. Particular attention will be given to etiologies lacking specific therapies, like viral hemorrhagic fevers, which pose unique risks to military personnel. The initiative seeks to address Department of Defense (DoD) capability gaps, enhance clinical management, and investigate the immunopathogenesis of infectious etiologies to improve severe sepsis outcomes in challenging environments.
Opportunity ID: 237915
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | N62645-PA-13-1 |
| Funding Opportunity Title: | Austere Environment Consortium for Enhanced Sepsis Outcomes (ACESO) Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | CategoryExplanation |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 12.340 — Naval Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 18, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Aug 30, 2013 |
| Current Closing Date for Applications: | Aug 30, 2013 |
| Archive Date: | Sep 29, 2013 |
| Estimated Total Program Funding: | $26,300,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | NAVAL MEDICAL LOGISTICS COMMAND |
| Description: | Overview: The Department of the Navy, Bureau of Medicine and Surgery (BUMED) is interested in receiving applications for a new Naval Medical Research Center (NMRC) program dedicated to improving prevention, early recognition, diagnosis, and effective treatment of severe sepsis from all causes in austere environments. This program will be supported through the establishment of a consortium of investigators with skills and expertise in infectious disease, critical care, systems biology, global health, and other relevant fields who will work together on a coordinated program of research. This consortium, named the Austere Environments Consortium for Enhanced Sepsis Outcomes (ACESO), will focus on the generation of knowledge that can rapidly translate into preventing and improving the outcome of severe sepsis in austere or resource-limited settings. Particular attention will focus on etiologic causes that currently have no specific therapies and that pose unique risks to the military with respect to outbreaks, deployed forces, or deliberate-use scenarios (e.g., viral hemorrhagic fever [VHF]). ACESO will establish a platform for research to address gaps in the Department of Defenses (DoD) capabilities for improving knowledge on severe sepsis and biological threats that manifest as severe sepsis in austere settings. ACESO will leverage a network of investigators, trained study staff, and in-country infrastructure to execute research that will evaluate clinical management strategies and the pathogenesis of severe sepsis, characterize the clinical aspects of sepsis related to various potential biological threats, improve outcomes for severe sepsis in austere environments, investigate the immunopathogenesis and long-term sequelae of infectious etiologies (especially hemorrhagic fevers), and augment the capability to gather important clinical data in outbreak settings of severe emerging disease. The ACESO award resulting from this program announcement will be issued as a cooperative agreement between the recipient (ACESO Coordinator) and the Government (the Naval Medical Logistics Command [NMLC]). One award is planned with a five year performance period. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NMLC RSD Help Desk
Email:NMLC-Research@med.navy.mil |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 237915 Full Announcement-1 -> aceso pa 18 july 2013.pdf
Packages
| Agency Contact Information: | NMLC RSD Help Desk
Email: NMLC-Research@med.navy.mil |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 12.340 | PKG00181230 | Jul 18, 2013 | Aug 30, 2013 | View |
Package 1
Mandatory forms
237915 RR_SF424_2_0-2.0.pdf
237915 RR_Budget_1_3-1.3.pdf
Optional forms
237915 RR_SubawardBudget_1_3-1.3.pdf
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