Opportunity ID: 293656

General Information

Document Type: Grants Notice
Funding Opportunity Number: W81XWH-17-ALSRP-TIA
Funding Opportunity Title: DoD ALSRP Therapeutic Idea Award
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Grant
Category of Funding Activity: Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards: 4
Assistance Listings: 12.420 — Military Medical Research and Development
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: May 05, 2017
Last Updated Date:
Original Closing Date for Applications: Aug 31, 2017
Current Closing Date for Applications: Aug 31, 2017
Archive Date: Sep 30, 2017
Estimated Total Program Funding: $3,200,000
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility:

Additional Information

Agency Name: Dept. of the Army — USAMRAA
Description: The Therapeutic Idea Award is designed to promote new ideas aimed at drug or treatment discovery that are still in the early stages of development. Development, modification, and/or validation of preclinical model systems or the application of high-throughput screens to define or assess lead compounds for ALS treatment are of interest. Parallel development of methods to measure either target binding or proximal downstream effects (target engagement) and the potential for undesirable activities at related but unintended targets (selectivity) are encouraged. All proposed research projects should include a well-formulated, testable hypothesis based on strong scientific rationale that holds translational potential to improve ALS treatment and/or advance a novel treatment modality. Projects that focus primarily on investigating the pathophysiology of ALS are outside the scope of this Program Announcement/Funding Opportunity.

Applicants seeking support for the development of products beyond drug or treatment discovery should consider the FY17 ALSRP Therapeutic Development Award (Funding Opportunity Number: W81XWH-17-ALSRP-TDA), which supports advanced preclinical development activities (http://cdmrp.army.mil/funding/alsrp).
Innovation and impact are important aspects of the Therapeutic Idea Award. Research deemed innovative may introduce a new paradigm, challenge current paradigms, introduce novel concepts or technologies, or exhibit other uniquely creative qualities that may lead to potential therapeutics for ALS. Research must also have the potential for a major impact and accelerate progress toward treatment for ALS. The impact may be near-term or long-term, but must be significant and move beyond an incremental advancement. Applications must articulate the pathway to making a clinical impact for individuals with, or at risk for, ALS, even if clinical impact is not an immediate outcome. Presentation of preliminary data is not consistent with the intent of the Therapeutic Idea Award mechanism. While the inclusion of preliminary data is not prohibited, the strength of the application should not rely on preliminary data, but on the innovative idea and the potential impact it will provide.

The Therapeutic Idea Award encourages applications that include meaningful and productive collaborations between investigators. As appropriate, applicants are encouraged to collaborate with industry partners and/or established ALS researchers.

Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

CDMRP Help Desk

Phone: 301-682-5507

Email: help@eBRAP.org
Email:help@eBRAP.org

Version History

Version Modification Description Updated Date

Folder 293656 Full Announcement-FY17 ALSRP TIA -> ALSRP_FY17_TIA_PA_GG.pdf

Packages

Agency Contact Information: CDMRP Help Desk
Phone: 301-682-5507
Email: help@eBRAP.org
Email: help@eBRAP.org
Who Can Apply: Organization Applicants

Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
12.420 PKG00232337 May 05, 2017 Aug 31, 2017 View

Package 1

Mandatory forms

293656 RR_SF424_2_0-2.0.pdf

293656 RR_Budget_1_4-1.4.pdf

293656 RR_KeyPersonExpanded_2_0-2.0.pdf

293656 PerformanceSite_2_0-2.0.pdf

293656 AttachmentForm_1_2-1.2.pdf

Optional forms

293656 RR_SubawardBudget30_1_4-1.4.pdf

2025-07-13T09:01:45-05:00

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