The Federal Small Business Innovative Research (SBIR) Program is offering this grant to small business concerns to develop novel medium- to high-throughput assays. These assays will evaluate the effects of chemical toxicants on the differentiation of pluripotent or induced pluripotent cells, ideally incorporating genetic diversity. This grant is for the purpose of advancing toxicology by providing information on chemically-induced biological activity mechanisms, prioritizing chemicals for extensive evaluation, and supporting more predictive in vivo models. The research will also inform the role of genetic diversity in toxicological effects, enhancing our understanding and assessment of chemical safety.
Opportunity ID: 205853
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-ES-13-003 |
| Funding Opportunity Title: | Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (SBIR [R43]) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Environment Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 06, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Feb 14, 2013 |
| Current Closing Date for Applications: | Feb 14, 2013 |
| Archive Date: | Mar 17, 2013 |
| Estimated Total Program Funding: | $2,500,000 |
| Award Ceiling: | $225,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) solicits Small Business Innovative Research (SBIR) grant applications from small business concerns (SBCs) to develop medium- to high-throughput assays to evaluate the effects of toxicants on pluripotent or induced pluripotent cells with respect to cell differentiation and the resulting differentiated cell populations. The ability to incorporate genetic diversity in these assays would be useful. These assays will provide information on mechanisms of chemically-induced biological activity, help to prioritize chemicals for more extensive toxicological evaluation, support more predictive models of in vivo biological response, and potentially inform on the role of genetic diversity in toxicological effects. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-13-003.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.113 | ADOBE-FORMS-B2 | Adobe-Forms-B2 | PKG00151131 | Jan 14, 2013 | Feb 14, 2013 | View |
Package 1
Mandatory forms
205853 RR_SF424_1_2-1.2.pdf
205853 PerformanceSite_1_4-1.4.pdf
205853 RR_OtherProjectInfo_1_3-1.3.pdf
205853 RR_KeyPersonExpanded_1_2-1.2.pdf
205853 RR_Budget-1.1.pdf
205853 PHS398_CoverPageSupplement_1_4-1.4.pdf
205853 PHS398_ResearchPlan_1_3-1.3.pdf
205853 PHS398_Checklist_1_3-1.3.pdf
205853 SBIR_STTR_Information_1_1-1.1.pdf
Optional forms
205853 RR_SubawardBudget30-1.2.pdf
205853 PHS_CoverLetter_1_2-1.2.pdf
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