This grant opportunity, offered as an R21 NOFO, aims to foster the development of novel theories and methods. Its primary purpose is to enhance our understanding of how genetic and non-genetic factors collectively influence the variation of complex human traits across diverse individuals, families, and populations. Successful approaches should embrace interdisciplinary collaboration, bridging the natural and social sciences. Projects are expected to consider the intricate interdependencies across biological, social, and ecological levels of organization. Applicants must propose robust methodologies that extensively utilize theoretical frameworks, sophisticated simulations, and rigorous validation processes, leveraging existing large-scale datasets. This funding is designed to advance innovative research in the genetic architecture of complex traits.
Opportunity ID: 350333
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-23-301 |
| Funding Opportunity Title: | Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.172 — Human Genome Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Sep 26, 2023 |
| Last Updated Date: | Nov 15, 2024 |
| Original Closing Date for Applications: | Jan 07, 2027 |
| Current Closing Date for Applications: | Nov 14, 2024 |
| Archive Date: | Dec 14, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $275,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Public and State controlled institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses State governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
The goal of this NOFO is to support R21 applications for novel theory and methods development that better delineate how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary across the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, simulations, and validation using available large-scale datasets |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-23-301.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Update close date per reissued NOFO PAR-25-256. | Nov 15, 2024 | |
| Sep 26, 2023 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-23-301 |
| Funding Opportunity Title: | Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.172 — Human Genome Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Sep 26, 2023 |
| Last Updated Date: | Nov 15, 2024 |
| Original Closing Date for Applications: | Jan 07, 2027 |
| Current Closing Date for Applications: | Nov 14, 2024 |
| Archive Date: | Dec 14, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $275,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Public and State controlled institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses State governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
The goal of this NOFO is to support R21 applications for novel theory and methods development that better delineate how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary across the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, simulations, and validation using available large-scale datasets |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-23-301.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-23-301 |
| Funding Opportunity Title: | Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.172 — Human Genome Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 26, 2023 |
| Last Updated Date: | Sep 26, 2023 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Jan 07, 2027 |
| Archive Date: | Feb 12, 2027 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $275,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) City or township governments Public and State controlled institutions of higher education Small businesses Private institutions of higher education State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Independent school districts County governments Special district governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of this NOFO is to support R21 applications for novel theory and methods development that better delineate how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary across the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, simulations, and validation using available large-scale datasets |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-23-301.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Related Documents
Folder 350333 Full Announcement-PAR-23-301 -> PAR-23-301-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283253 | Jan 16, 2024 | Nov 18, 2024 | View | |
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288912 | Nov 08, 2024 | Jan 07, 2027 | View |
Package 1
Mandatory forms
350333 RR_SF424_5_0-5.0.pdf
350333 PHS398_CoverPageSupplement_5_0-5.0.pdf
350333 RR_OtherProjectInfo_1_4-1.4.pdf
350333 PerformanceSite_4_0-4.0.pdf
350333 RR_KeyPersonExpanded_4_0-4.0.pdf
350333 PHS398_ResearchPlan_5_0-5.0.pdf
350333 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350333 RR_Budget_3_0-3.0.pdf
350333 RR_SubawardBudget30_3_0-3.0.pdf
350333 PHS398_ModularBudget_1_2-1.2.pdf
350333 PHS_AssignmentRequestForm_4_0-4.0.pdf
Package 2
Mandatory forms
350333 RR_SF424_5_0-5.0.pdf
350333 PHS398_CoverPageSupplement_5_0-5.0.pdf
350333 RR_OtherProjectInfo_1_4-1.4.pdf
350333 PerformanceSite_4_0-4.0.pdf
350333 RR_KeyPersonExpanded_4_0-4.0.pdf
350333 PHS398_ResearchPlan_5_0-5.0.pdf
350333 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350333 RR_Budget_3_0-3.0.pdf
350333 RR_SubawardBudget30_3_0-3.0.pdf
350333 PHS398_ModularBudget_1_2-1.2.pdf
350333 PHS_AssignmentRequestForm_3_0-3.0.pdf
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