Health and Human Services Department: Biomarkers for Pediatric and Adult Therapeutics Grant (R01)

The Health and Human Services Department is offering the Biomarkers for Pediatric and Adult Therapeutics Grant (R01) to adapt adult biomarkers for pediatric use. This grant focuses on validating biomarkers from adults for pediatric diagnosis, prognosis, disease progression, toxicity, and therapy response. Projects should utilize biomarkers with proven adult applications and clinical correlation. Not included are biomarkers for new drug development, unique pediatric diseases without adult counterparts, or preclinical studies. Applications for this grant close on Sep 07, 2016.

Opportunity ID: 239017

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	PAR-13-296
Funding Opportunity Title::	Biomarkers: Bridging Pediatric and Adult Therapeutics (R01)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Health
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.865 — Child Health and Human Development Extramural Research
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Aug 01, 2013
Last Updated Date::
Original Closing Date for Applications::	Sep 07, 2016
Current Closing Date for Applications::	Sep 07, 2016
Archive Date::	Oct 08, 2016
Estimated Total Program Funding::
Award Ceiling::	$
Award Floor::	$

Eligibility

Eligible Applicants::

Public and State controlled institutions of higher education

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	This Funding Opportunity Announcement (FOA) encourages grant applications that propose adapting adult biomarkers to children. This would include the application and validation of biomarkers developed in adults to pediatric diagnosis, prognosis, and estimation of disease progression, toxicity and response to therapy. Projects supported by this FOA will be confined to those biomarkers that correlate with a clinical observation, have been extensively studied in adults, and for which there is solid evidence that they have pediatric applications. Discovery of new biomarkers for use in new drug development or in preclinical studies is not part of this FOA. Also excluded are biomarkers for diseases that are unique to children and have no adult correlates.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:	93.865
Competition ID:	FORMS-C
Competition Title:	Forms-C
Opportunity Package ID:	PKG00182295
Opening Date:	Sep 05, 2013
Closing Date:	May 07, 2016
Agency Contact Information::	eRA Commons Help Desk
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3]