Opportunity ID: 269798

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-ES-15-006
Funding Opportunity Title: Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (R43/R44)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Environment
Health
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.113 — Environmental Health
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Nov 24, 2014
Last Updated Date: Jan 27, 2015
Original Closing Date for Applications: Feb 13, 2015
Current Closing Date for Applications: Feb 19, 2015
Archive Date: Mar 19, 2015
Estimated Total Program Funding: $3,000,000
Award Ceiling: $225,000
Award Floor:

Eligibility

Eligible Applicants: Small businesses
Additional Information on Eligibility: Other Eligible Applicants include the following:
1. Is organized for profit, with a place of business located in the United States, which operates primarily within the United States or which makes a significant contribution to the United States economy through payment of taxes or use of American products, materials or labor;

2. Is in the legal form of an individual proprietorship, partnership, limited liability company, corporation, joint venture, association, trust or cooperative, except that where the form is a joint venture, there must be less than 50 percent participation by foreign business entities in the joint venture;

3.
i. SBIR and STTR. Be a concern which is more than 50% directly owned and controlled by one or more individuals (who are citizens or permanent resident aliens of the United States), other business concerns (each of which is more than 50% directly owned and controlled by individuals who are citizens or permanent resident aliens of the United States), or any combination of these; OR

ii. SBIR-only. Be a concern which is more than 50% owned by multiple venture capital operating companies, hedge funds, private equity firms, or any combination of these. No single venture capital operating company, hedge fund, or private equity firm may own more than 50% of the concern; OR

iii. SBIR and STTR. Be a joint venture in which each entity to the joint venture must meet the requirements set forth in paragraph 3 (i) or 3 (ii) of this section. A joint venture that includes one or more concerns that meet the requirements of paragraph (ii) of this section must comply with § 121.705(b) concerning registration and proposal requirements.

4. Has, including its affiliates, not more than 500 employees.

Additional Information

Agency Name: National Institutes of Health
Description: This Funding Opportunity Announcement (FOA) solicits Small Business Innovative Research (SBIR) grant applications from small business concerns (SBCs) to develop medium- to high-throughput assays to evaluate the effects of toxicants on pluripotent or induced pluripotent cells with respect to cell differentiation and the resulting differentiated cell populations. The ability to incorporate genetic diversity in these assays would be useful.These assays will provide information on mechanisms of chemically-induced biological activity, help to prioritize chemicals for more extensive toxicological evaluation, support more predictive models of in vivo biological response, and potentially inform on the role of genetic diversity in toxicological effects.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-15-006.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster

FBOWebmaster@OD.NIH.GOV

Email:FBOWebmaster@OD.NIH.GOV

Version History

Version Modification Description Updated Date
Modified to update the close date field, in accordance with the NIH Guide NOT-OD-15-057. Jan 27, 2015
Jan 27, 2015

DISPLAYING: Synopsis 2

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-ES-15-006
Funding Opportunity Title: Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (R43/R44)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Environment
Health
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.113 — Environmental Health
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Nov 24, 2014
Last Updated Date: Jan 27, 2015
Original Closing Date for Applications: Feb 13, 2015
Current Closing Date for Applications: Feb 19, 2015
Archive Date: Mar 19, 2015
Estimated Total Program Funding: $3,000,000
Award Ceiling: $225,000
Award Floor:

Eligibility

Eligible Applicants: Small businesses
Additional Information on Eligibility: Other Eligible Applicants include the following:
1. Is organized for profit, with a place of business located in the United States, which operates primarily within the United States or which makes a significant contribution to the United States economy through payment of taxes or use of American products, materials or labor;

2. Is in the legal form of an individual proprietorship, partnership, limited liability company, corporation, joint venture, association, trust or cooperative, except that where the form is a joint venture, there must be less than 50 percent participation by foreign business entities in the joint venture;

3.
i. SBIR and STTR. Be a concern which is more than 50% directly owned and controlled by one or more individuals (who are citizens or permanent resident aliens of the United States), other business concerns (each of which is more than 50% directly owned and controlled by individuals who are citizens or permanent resident aliens of the United States), or any combination of these; OR

ii. SBIR-only. Be a concern which is more than 50% owned by multiple venture capital operating companies, hedge funds, private equity firms, or any combination of these. No single venture capital operating company, hedge fund, or private equity firm may own more than 50% of the concern; OR

iii. SBIR and STTR. Be a joint venture in which each entity to the joint venture must meet the requirements set forth in paragraph 3 (i) or 3 (ii) of this section. A joint venture that includes one or more concerns that meet the requirements of paragraph (ii) of this section must comply with § 121.705(b) concerning registration and proposal requirements.

4. Has, including its affiliates, not more than 500 employees.

Additional Information

Agency Name: National Institutes of Health
Description: This Funding Opportunity Announcement (FOA) solicits Small Business Innovative Research (SBIR) grant applications from small business concerns (SBCs) to develop medium- to high-throughput assays to evaluate the effects of toxicants on pluripotent or induced pluripotent cells with respect to cell differentiation and the resulting differentiated cell populations. The ability to incorporate genetic diversity in these assays would be useful.These assays will provide information on mechanisms of chemically-induced biological activity, help to prioritize chemicals for more extensive toxicological evaluation, support more predictive models of in vivo biological response, and potentially inform on the role of genetic diversity in toxicological effects.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-15-006.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster

FBOWebmaster@OD.NIH.GOV

Email:FBOWebmaster@OD.NIH.GOV

DISPLAYING: Synopsis 1

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-ES-15-006
Funding Opportunity Title: Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (R43/R44)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Environment
Health
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.113 — Environmental Health
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Jan 27, 2015
Last Updated Date:
Original Closing Date for Applications:
Current Closing Date for Applications: Feb 13, 2015
Archive Date: Mar 16, 2015
Estimated Total Program Funding: $3,000,000
Award Ceiling: $225,000
Award Floor:

Eligibility

Eligible Applicants: Small businesses
Additional Information on Eligibility: Other Eligible Applicants include the following:
1. Is organized for profit, with a place of business located in the United States, which operates primarily within the United States or which makes a significant contribution to the United States economy through payment of taxes or use of American products, materials or labor;

2. Is in the legal form of an individual proprietorship, partnership, limited liability company, corporation, joint venture, association, trust or cooperative, except that where the form is a joint venture, there must be less than 50 percent participation by foreign business entities in the joint venture;

3.
i. SBIR and STTR. Be a concern which is more than 50% directly owned and controlled by one or more individuals (who are citizens or permanent resident aliens of the United States), other business concerns (each of which is more than 50% directly owned and controlled by individuals who are citizens or permanent resident aliens of the United States), or any combination of these; OR

ii. SBIR-only. Be a concern which is more than 50% owned by multiple venture capital operating companies, hedge funds, private equity firms, or any combination of these. No single venture capital operating company, hedge fund, or private equity firm may own more than 50% of the concern; OR

iii. SBIR and STTR. Be a joint venture in which each entity to the joint venture must meet the requirements set forth in paragraph 3 (i) or 3 (ii) of this section. A joint venture that includes one or more concerns that meet the requirements of paragraph (ii) of this section must comply with § 121.705(b) concerning registration and proposal requirements.

4. Has, including its affiliates, not more than 500 employees.

Additional Information

Agency Name: National Institutes of Health
Description: This Funding Opportunity Announcement (FOA) solicits Small Business Innovative Research (SBIR) grant applications from small business concerns (SBCs) to develop medium- to high-throughput assays to evaluate the effects of toxicants on pluripotent or induced pluripotent cells with respect to cell differentiation and the resulting differentiated cell populations. The ability to incorporate genetic diversity in these assays would be useful.These assays will provide information on mechanisms of chemically-induced biological activity, help to prioritize chemicals for more extensive toxicological evaluation, support more predictive models of in vivo biological response, and potentially inform on the role of genetic diversity in toxicological effects.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-15-006.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV

Email:FBOWebmaster@OD.NIH.GOV

Related Documents

Packages

Agency Contact Information: NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV

Email: FBOWebmaster@OD.NIH.GOV

Who Can Apply: Organization Applicants

Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
FORMS-C FORMS-C PKG00210087 Jan 13, 2015 Feb 19, 2015 View

Package 1

Mandatory forms

269798 RR_SF424_2_0-2.0.pdf

269798 PHS398_ResearchPlan_2_0-2.0.pdf

269798 SBIR_STTR_Information_1_1-1.1.pdf

269798 RR_KeyPersonExpanded_2_0-2.0.pdf

269798 RR_OtherProjectInfo_1_3-1.3.pdf

269798 RR_Budget_1_3-1.3.pdf

269798 PerformanceSite_2_0-2.0.pdf

269798 PHS398_CoverPageSupplement_2_0-2.0.pdf

Optional forms

269798 RR_SubawardBudget30_1_3-1.3.pdf

269798 PlannedReport-1.0.pdf

269798 PHS398_CumulativeInclusionReport-1.0.pdf

2025-07-09T20:25:22-05:00

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