Health Department Grant: Addressing Inflammation and Immune Activation in HIV Disease (U01)

This grant from the Health Department aims to support small proof-of-concept clinical trials and intensive laboratory studies focusing on the impact of interventions on chronic immune activation and inflammation in HIV-infected individuals on antiretroviral therapy. The intervention must have a defined mechanism of action. The ultimate objective is to pinpoint targeted mechanisms or pathways that could combat persistent immune activation in HIV patients.

Opportunity ID: 139093

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	RFA-AI-12-007
Funding Opportunity Title::	Targeting Inflammation and Immune Activation in HIV Disease (U01)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Health
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.855 — Allergy, Immunology and Transplantation Research
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Jan 20, 2012
Last Updated Date::
Original Closing Date for Applications::	Jul 13, 2012
Current Closing Date for Applications::	Jul 13, 2012
Archive Date::	Aug 13, 2012
Estimated Total Program Funding::	$ 2,300,000
Award Ceiling::	$
Award Floor::	$

Eligibility

Eligible Applicants::

Others (see text field entitled “Additional Information on Eligibility” for clarification)

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	This FOA solicits applications that propose small proof-of-concept clinical trials, with concurrent intensive laboratory studies, designed to evaluate the effect of an intervention on chronic immune activation or persistent inflammation in HIV-infected individuals who are taking effective antiretroviral therapy. The intervention must have a known mechanism of action. The goal of this initiative is to identify specific mechanisms or pathways that can be targeted to prevent or reverse persistent immune activation in HIV-infected individuals.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID:	ADOBE-FORMS-B2
Competition Title:	ADOBE-FORMS-B2
Opportunity Package ID:	PKG00092610
Opening Date:	Jun 13, 2012
Closing Date:	Jul 13, 2012
Agency Contact Information::	Grants Info
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2]