This grant from health research agencies establishes Cooperative Research Centers (CRCs) for developing Clostridioides difficile infection (CDI) vaccines. It supports multidisciplinary investigations into the host immune response to CDI. Research will leverage clinical samples, identify new protective antigens, and utilize novel vaccine and adjuvant platforms. The objective is to advance immunity knowledge against CDI. Insights will guide the creation of next-generation C. difficile vaccines, to be tested in model systems, ultimately fostering collaborative efforts for combating CDI through advanced immunological strategies.
Opportunity ID: 337268
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-22-001 |
| Funding Opportunity Title: | Host Immunity and Novel Immunization Strategies for Clostridioides difficile Infection (CDI) (U19 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 07, 2022 |
| Last Updated Date: | Jan 07, 2022 |
| Original Closing Date for Applications: | May 20, 2022 |
| Current Closing Date for Applications: | May 20, 2022 |
| Archive Date: | Jun 25, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $1,000,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses State governments Special district governments City or township governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education County governments Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to support the formation of Cooperative Research Centers (CRCs) to pursue vaccine development through multidisciplinary investigations into the host immune response to Clostridioides difficile infection (CDI). To this end, it will be critical to advance knowledge of immunity against CDI by leveraging clinical samples, identifying new protective antigens, and employing novel vaccine and adjuvant platforms. Information stemming from this research initiative will serve as a guide to develop the next generation of C. difficile vaccines to be tested in appropriately devised model systems |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-22-001.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 337268 Full Announcement-RFA-AI-22-001 -> RFA-AI-22-001-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00271271 | Apr 20, 2022 | May 20, 2022 | View |
Package 1
Mandatory forms
337268 RR_SF424_5_0-5.0.pdf
337268 PHS398_CoverPageSupplement_5_0-5.0.pdf
337268 RR_OtherProjectInfo_1_4-1.4.pdf
337268 PerformanceSite_4_0-4.0.pdf
337268 RR_KeyPersonExpanded_4_0-4.0.pdf
337268 PHS398_ResearchPlan_4_0-4.0.pdf
337268 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
337268 PHS_Additional_IndirectCosts_2_0-2.0.pdf
337268 PHS_AssignmentRequestForm_3_0-3.0.pdf
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