Opportunity ID: 325699

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-HG-20-001
Funding Opportunity Title: Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry Centers (U01 Clinical Trial Not Allowed)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.172 — Human Genome Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Mar 23, 2020
Last Updated Date: May 26, 2020
Original Closing Date for Applications: Jun 23, 2020
Current Closing Date for Applications: Jul 07, 2020
Archive Date: Aug 06, 2020
Estimated Total Program Funding: $6,000,000
Award Ceiling: $1,000,000
Award Floor:

Eligibility

Eligible Applicants: Native American tribal organizations (other than Federally recognized tribal governments)
Special district governments
Small businesses
City or township governments
Public and State controlled institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
County governments
Private institutions of higher education
Public housing authorities/Indian housing authorities
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Independent school districts
For profit organizations other than small businesses
Native American tribal governments (Federally recognized)
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description:

The goal of the intended FOA is to establish Centers for PRS Methods and Analysis for Populations of Diverse Ancestry to collaboratively generate and refine PRS for populations of diverse ancestry by integrating existing datasets with genomic and phenotype data for a range of complex diseases and traits. Together with a Coordinating Center (described in a separate FOA), grantees funded under the intended FOA will form a Consortium with the primary objectives of: 1) leveraging genetic diversity to develop methods and improve the applicability of PRS to predict health and disease risk across diverse populations, and for a broad range of health and disease measures; and 2) optimizing the integration of large-scale, harmonized genomic and phenotype data to facilitate collaborative analysis, dissemination of PRS-related data, and development of related methods and resources.

Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-20-001.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster

FBOWebmaster@OD.NIH.GOV
Email:FBOWebmaster@OD.NIH.GOV

Version History

Version Modification Description Updated Date
updated close date May 26, 2020
Mar 23, 2020
Apr 06, 2020

DISPLAYING: Synopsis 2

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-HG-20-001
Funding Opportunity Title: Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry Centers (U01 Clinical Trial Not Allowed)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.172 — Human Genome Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Mar 23, 2020
Last Updated Date: May 26, 2020
Original Closing Date for Applications: Jun 23, 2020
Current Closing Date for Applications: Jul 07, 2020
Archive Date: Aug 06, 2020
Estimated Total Program Funding: $6,000,000
Award Ceiling: $1,000,000
Award Floor:

Eligibility

Eligible Applicants: Native American tribal organizations (other than Federally recognized tribal governments)
Special district governments
Small businesses
City or township governments
Public and State controlled institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
County governments
Private institutions of higher education
Public housing authorities/Indian housing authorities
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Independent school districts
For profit organizations other than small businesses
Native American tribal governments (Federally recognized)
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description:

The goal of the intended FOA is to establish Centers for PRS Methods and Analysis for Populations of Diverse Ancestry to collaboratively generate and refine PRS for populations of diverse ancestry by integrating existing datasets with genomic and phenotype data for a range of complex diseases and traits. Together with a Coordinating Center (described in a separate FOA), grantees funded under the intended FOA will form a Consortium with the primary objectives of: 1) leveraging genetic diversity to develop methods and improve the applicability of PRS to predict health and disease risk across diverse populations, and for a broad range of health and disease measures; and 2) optimizing the integration of large-scale, harmonized genomic and phenotype data to facilitate collaborative analysis, dissemination of PRS-related data, and development of related methods and resources.

Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-20-001.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster

FBOWebmaster@OD.NIH.GOV
Email:FBOWebmaster@OD.NIH.GOV

DISPLAYING: Synopsis 1

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-HG-20-001
Funding Opportunity Title: Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry Centers (U01 Clinical Trial Not Allowed)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.172 — Human Genome Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Mar 23, 2020
Last Updated Date: Mar 23, 2020
Original Closing Date for Applications:
Current Closing Date for Applications: Jun 23, 2020
Archive Date: Jul 29, 2020
Estimated Total Program Funding: $6,000,000
Award Ceiling: $1,000,000
Award Floor:

Eligibility

Eligible Applicants: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
City or township governments
State governments
Native American tribal governments (Federally recognized)
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Independent school districts
Private institutions of higher education
Public and State controlled institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
County governments
Special district governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
Small businesses
Public housing authorities/Indian housing authorities
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: The goal of the intended FOA is to establish Centers for PRS Methods and Analysis for Populations of Diverse Ancestry to collaboratively generate and refine PRS for populations of diverse ancestry by integrating existing datasets with genomic and phenotype data for a range of complex diseases and traits. Together with a Coordinating Center (described in a separate FOA), grantees funded under the intended FOA will form a Consortium with the primary objectives of: 1) leveraging genetic diversity to develop methods and improve the applicability of PRS to predict health and disease risk across diverse populations, and for a broad range of health and disease measures; and 2) optimizing the integration of large-scale, harmonized genomic and phenotype data to facilitate collaborative analysis, dissemination of PRS-related data, and development of related methods and resources.
Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-20-001.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV
Email:FBOWebmaster@OD.NIH.GOV

DISPLAYING: Forecast 1

General Information

Document Type: Grants Notice
Funding Opportunity Number: NOT-HG-20-005
Funding Opportunity Title: Notice of Intent to Publish a Funding Opportunity Announcement for Centers for Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry (U01 Clinical Trial Not Allowed)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards: 3
Assistance Listings: 93.172 — Human Genome Research
Cost Sharing or Matching Requirement: No
Version: Forecast 1
Posted Date: Apr 06, 2020
Last Updated Date:
Original Closing Date for Applications:
Current Closing Date for Applications:
Archive Date: Mar 22, 2020
Estimated Total Program Funding: $25,000,000
Award Ceiling: $1,000,000
Award Floor:

Eligibility

Eligible Applicants: Private institutions of higher education
Public and State controlled institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
County governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
Small businesses
State governments
Native American tribal governments (Federally recognized)
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Additional Information on Eligibility:

Additional Information

Agency Name:
Description: The National Human Genome Research Institute intends to issue a Funding Opportunity Announcement (FOA) to solicit applications to support Centers for Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry. The intended FOA will be based on a concept recently approved by the National Advisory Council on Human Genome Research and accompanying discussion (https://www.genome.gov/sites/default/files/media/files/2019-09/Sept2019_Council_Hindorff_PolygenicRiskScore_RFA_Concept.pdf and https://www.youtube.com/watch?v=x0-hw7DoOQU).
This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.
The FOA is expected to be published in January, 2020 with an expected application due date in Summer, 2020.
This FOA will utilize the U01 activity code. Details of the planned FOA are provided below.
Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:


Email:hindorffl@mail.nih.gov

Related Documents

Packages

Agency Contact Information: NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV
Email: FBOWebmaster@OD.NIH.GOV
Who Can Apply: Organization Applicants

Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
FORMS-F Use for due dates on or after May 25, 2020 PKG00260433 May 23, 2020 Jul 07, 2020 View

Package 1

Mandatory forms

325699 RR_SF424_2_0-2.0.pdf

325699 PHS398_CoverPageSupplement_5_0-5.0.pdf

325699 RR_OtherProjectInfo_1_4-1.4.pdf

325699 PerformanceSite_2_0-2.0.pdf

325699 RR_KeyPersonExpanded_2_0-2.0.pdf

325699 PHS398_ResearchPlan_4_0-4.0.pdf

325699 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf

Optional forms

325699 RR_Budget_1_4-1.4.pdf

325699 RR_SubawardBudget30_1_4-1.4.pdf

325699 PHS398_ModularBudget_1_2-1.2.pdf

325699 PHS_AssignmentRequestForm_3_0-3.0.pdf

2025-07-14T11:18:49-05:00

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