This grant is offered by a Health Research Department to accelerate crucial research focused on developing effective in utero treatments for congenital dental and craniofacial disorders. The initiative specifically encourages projects utilizing advanced animal models and precision medicine approaches to discover and refine therapeutic interventions. The core purpose is to establish robust foundational knowledge and methodologies. This foundational work is critical for paving the way for the eventual translation and safe delivery of these innovative in utero treatments in human patients, ultimately addressing significant developmental health challenges from an early stage. This supports preclinical development, a vital step before human trials.
Opportunity ID: 338118
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DE-23-005 |
| Funding Opportunity Title: | In utero Treatments of Congenital Dental and Craniofacial Disorders Using Precision Medicine Approaches (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 16, 2022 |
| Last Updated Date: | Feb 16, 2022 |
| Original Closing Date for Applications: | Jun 14, 2022 |
| Current Closing Date for Applications: | Jun 14, 2022 |
| Archive Date: | Jul 20, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Small businesses For profit organizations other than small businesses Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Private institutions of higher education Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments City or township governments Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This initiative is intended to accelerate research using animal models and precision medicine approaches to develop in utero treatments of congenital dental and craniofacial disorders. The long-term goal is to lay the groundwork for delivery of in utero treatments in human. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DE-23-005.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 338118 Full Announcement-RFA-DE-23-005 -> RFA-DE-23-005-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00272097 | May 16, 2022 | Jun 14, 2022 | View |
Package 1
Mandatory forms
338118 RR_SF424_5_0-5.0.pdf
338118 PHS398_CoverPageSupplement_5_0-5.0.pdf
338118 RR_OtherProjectInfo_1_4-1.4.pdf
338118 PerformanceSite_4_0-4.0.pdf
338118 RR_KeyPersonExpanded_4_0-4.0.pdf
338118 PHS398_ResearchPlan_4_0-4.0.pdf
338118 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338118 RR_Budget_3_0-3.0.pdf
338118 RR_SubawardBudget30_3_0-3.0.pdf
338118 PHS398_ModularBudget_1_2-1.2.pdf
338118 PHS_AssignmentRequestForm_3_0-3.0.pdf