The Human Islet Research Network (HIRN) Human Pancreas Analysis Consortium (HPAC) is offering this cooperative agreement grant. This grant is for contributing to a higher resolution understanding of the human pancreatic tissue environment. It aims to describe the composition and function of important components of the pancreatic islet and peri-islet tissue architecture. Furthermore, it seeks to investigate cell-cell relationships and communication within the pancreatic tissue ecosystem, and explore the contribution of adjacent tissues to islet cell function and dysfunction. Successful projects will integrate with the existing HPAC. HIRN’s overall mission is to support innovative research to understand human beta cell loss in Type 1 Diabetes and find strategies to protect or replace functional beta cell mass in humans. This funding exclusively supports studies primarily focused on increasing knowledge of human tissue structure, function, and disease biology, specifically excluding animal models.
Opportunity ID: 335295
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-21-017 |
| Funding Opportunity Title: | High-Resolution Exploration of the Human Islet Tissue Environment [HIRN Human Pancreas Analysis Consortium (HPAC)] (U01 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 12, 2021 |
| Last Updated Date: | Aug 12, 2021 |
| Original Closing Date for Applications: | Mar 03, 2022 |
| Current Closing Date for Applications: | Mar 03, 2022 |
| Archive Date: | Apr 08, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $600,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Small businesses City or township governments State governments For profit organizations other than small businesses Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites cooperative agreement applications that will contribute to a higher resolution understanding of the organization of the human pancreatic tissue environment by describing the composition and function of important components of the pancreatic islet and peri-islet tissue architecture, the cell-cell relationships and means of communications used by cell types and cell subtypes within the pancreatic tissue ecosystem, and the contribution of adjacent tissues to islet cell function and dysfunction. Successful projects will integrate the Human Pancreas Analysis Consortium (HPAC) that is part of the Human Islet Research Network or HIRN (https://hirnetwork.org/). HIRN’s overall mission is to support innovative and collaborative translational research to understand how human beta cells are lost in T1D, and to find innovative strategies to protect and replace functional beta cell mass in humans. This FOA will only support studies with a primary focus on increasing our understanding of human tissue structure and function, and human disease biology, as opposed to exploring the biology specific to any animal models. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-21-017.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 335295 Full Announcement-RFA-DK-21-017 -> RFA-DK-21-017-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00270450 | Feb 03, 2022 | Mar 03, 2022 | View | |
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00268551 | Feb 03, 2022 | Jan 24, 2022 | View |
Package 1
Mandatory forms
335295 RR_SF424_5_0-5.0.pdf
335295 PHS398_CoverPageSupplement_5_0-5.0.pdf
335295 RR_OtherProjectInfo_1_4-1.4.pdf
335295 PerformanceSite_4_0-4.0.pdf
335295 RR_KeyPersonExpanded_4_0-4.0.pdf
335295 PHS398_ResearchPlan_4_0-4.0.pdf
335295 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
335295 RR_Budget_3_0-3.0.pdf
335295 RR_SubawardBudget30_3_0-3.0.pdf
335295 PHS398_ModularBudget_1_2-1.2.pdf
335295 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
335295 RR_SF424_2_0-2.0.pdf
335295 PHS398_CoverPageSupplement_5_0-5.0.pdf
335295 RR_OtherProjectInfo_1_4-1.4.pdf
335295 PerformanceSite_2_0-2.0.pdf
335295 RR_KeyPersonExpanded_2_0-2.0.pdf
335295 PHS398_ResearchPlan_4_0-4.0.pdf
335295 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
335295 RR_Budget_1_4-1.4.pdf
335295 RR_SubawardBudget30_1_4-1.4.pdf
335295 PHS398_ModularBudget_1_2-1.2.pdf
335295 PHS_AssignmentRequestForm_3_0-3.0.pdf
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