The Human Islet Research Network (HIRN) is offering this grant through its Consortium on Targeting and Regeneration (CTAR) to support cutting-edge research aimed at increasing or protecting functional human beta cell mass. This grant is specifically for developing innovative strategies for patients with Type-1 Diabetes (T1D). The focus areas include the controlled manipulation of beta cell replication, exploring islet cell plasticity, and reprogramming pancreatic non-beta cells into functional beta-like cells. Additionally, the grant supports research into methods for shielding existing beta cell mass from the destructive autoimmune environment inherent in T1D, all as part of the broader HIRN initiative.
Opportunity ID: 342205
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-22-009 |
| Funding Opportunity Title: | Human Islet Research Network – Consortium on Targeting and Regeneration (HIRN-CTAR) (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 13, 2022 |
| Last Updated Date: | Jul 13, 2022 |
| Original Closing Date for Applications: | Oct 26, 2022 |
| Current Closing Date for Applications: | Oct 26, 2022 |
| Archive Date: | Dec 01, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $600,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Small businesses Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Special district governments Independent school districts State governments County governments Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites applications for the Consortium on Targeting and Regeneration (CTAR) that supports the development of innovative strategies to increase or protect functional human beta cell mass in patients with Type-1 Diabetes (T1D) through the controlled manipulation of beta cell replication, islet cell plasticity, and the reprogramming of pancreatic non-beta cells into beta-like cells, or through shielding the residual beta cell mass from the autoimmune environment. CTAR is part of the Human Islet Research Network (HIRN). |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-22-009.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 342205 Full Announcement-RFA-DK-22-009 -> RFA-DK-22-009-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00275870 | Sep 26, 2022 | Oct 26, 2022 | View |
Package 1
Mandatory forms
342205 RR_SF424_5_0-5.0.pdf
342205 PHS398_CoverPageSupplement_5_0-5.0.pdf
342205 RR_OtherProjectInfo_1_4-1.4.pdf
342205 PerformanceSite_4_0-4.0.pdf
342205 RR_KeyPersonExpanded_4_0-4.0.pdf
342205 PHS398_ResearchPlan_4_0-4.0.pdf
342205 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
342205 RR_Budget_3_0-3.0.pdf
342205 RR_SubawardBudget30_3_0-3.0.pdf
342205 PHS398_ModularBudget_1_2-1.2.pdf
342205 PHS_AssignmentRequestForm_3_0-3.0.pdf
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