This grant, offered by the IGVF Consortium, seeks to establish Mapping Centers. These Centers will generate single-cell, multi-omics maps of active genes and regulatory elements in human and mouse genomes using high-throughput methods. The goal is to profile biochemical features while preserving biological/spatial context, enabling the association of active genomic regions with specific cell fates and states. As part of the Impact of Genomic Variation on Function (IGVF) Consortium, Centers will collaborate to accelerate understanding of genomic variation’s impact on human health and disease via coordinated data collection and analyses.
Opportunity ID: 328536
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HG-20-045 |
| Funding Opportunity Title: | Single-cell Profiling of Regulatory Element and Gene Activity in Relationship to Genome Function (UM1 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.172 — Human Genome Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 04, 2020 |
| Last Updated Date: | Aug 04, 2020 |
| Original Closing Date for Applications: | Nov 04, 2020 |
| Current Closing Date for Applications: | Nov 04, 2020 |
| Archive Date: | Dec 10, 2020 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts City or township governments County governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Special district governments Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to establish Mapping Centers that will generate single-cell, multi-omics maps of active genes and regulatory elements in the human and mouse genomes. This will be accomplished through use of high-throughput state-of-the-art methods to profile biochemical features characteristic of active genomic regions while preserving information about biological and/or spatial context. This will ultimately enable the association of active genomic regions with specific cell fates and states. Centers funded through this initiative will become part of the Impact of Genomic Variation on Function (IGVF) Consortium. As members of this consortium, Mapping Centers will be expected to work closely with one another and other Consortium components to accelerate understanding of how genomic variation impacts human health and disease through the coordination of data collection strategies and analyses. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-20-045.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00262876 | Oct 04, 2020 | Nov 04, 2020 | View |
Package 1
Mandatory forms
328536 RR_SF424_2_0-2.0.pdf
328536 PHS398_CoverPageSupplement_5_0-5.0.pdf
328536 RR_OtherProjectInfo_1_4-1.4.pdf
328536 PerformanceSite_2_0-2.0.pdf
328536 RR_KeyPersonExpanded_2_0-2.0.pdf
328536 RR_Budget_1_4-1.4.pdf
328536 PHS398_ResearchPlan_4_0-4.0.pdf
328536 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
328536 RR_SubawardBudget30_1_4-1.4.pdf
328536 PHS_AssignmentRequestForm_3_0-3.0.pdf
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