The Infectious Disease Research Department is offering this grant to support critical mechanistic studies focused on host cell death pathways and immune responses to Mycobacterium tuberculosis (Mtb) and Mtb/HIV co-infection. This grant is specifically designed to facilitate the identification of novel immune targets, which are crucial for the development of innovative host-directed therapies. The overarching purpose is to advance our understanding of how Mtb and Mtb/HIV interact with host cells, ultimately paving the way for more effective treatments for these challenging infections. Research supported by this grant will aim to uncover fundamental biological insights that can be translated into therapeutic strategies to combat the global health burden of Mtb and Mtb/HIV co-infection.
Opportunity ID: 343053
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-223 |
| Funding Opportunity Title: | Identifying Host Cell Death Pathway Targets for Host-Directed Therapies for Treatment of Mtb and Mtb/HIV Co-Infection (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 09, 2022 |
| Last Updated Date: | Aug 09, 2022 |
| Original Closing Date for Applications: | Dec 07, 2024 |
| Current Closing Date for Applications: | Dec 07, 2024 |
| Archive Date: | Jan 12, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Private institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Independent school districts Small businesses State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to support mechanistic studies on host cell death pathways and immune responses to Mycobacterium tuberculosis (Mtb) and Mtb/HIV co-infection to identify immune targets for development of host-directed therapies. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-22-223.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 343053 Full Announcement-PAR-22-223 -> PAR-22-223-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00276351 | Nov 07, 2022 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00277823 | Nov 07, 2022 | Jan 24, 2025 | View |
Package 1
Mandatory forms
343053 RR_SF424_5_0-5.0.pdf
343053 PHS398_CoverPageSupplement_5_0-5.0.pdf
343053 RR_OtherProjectInfo_1_4-1.4.pdf
343053 PerformanceSite_4_0-4.0.pdf
343053 RR_KeyPersonExpanded_4_0-4.0.pdf
343053 PHS398_ResearchPlan_4_0-4.0.pdf
343053 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343053 RR_Budget_3_0-3.0.pdf
343053 RR_SubawardBudget30_3_0-3.0.pdf
343053 PHS398_ModularBudget_1_2-1.2.pdf
343053 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
343053 RR_SF424_5_0-5.0.pdf
343053 PHS398_CoverPageSupplement_5_0-5.0.pdf
343053 RR_OtherProjectInfo_1_4-1.4.pdf
343053 PerformanceSite_4_0-4.0.pdf
343053 RR_KeyPersonExpanded_4_0-4.0.pdf
343053 PHS398_ResearchPlan_5_0-5.0.pdf
343053 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343053 RR_Budget_3_0-3.0.pdf
343053 RR_SubawardBudget30_3_0-3.0.pdf
343053 PHS398_ModularBudget_1_2-1.2.pdf
343053 PHS_AssignmentRequestForm_3_0-3.0.pdf
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