This grant opportunity, affiliated with the Kidney Precision Medicine Project (KPMP), seeks applications for Recruitment Sites (RS). The purpose of this grant is to establish new sites dedicated to enrolling adult and pediatric patients with Type 1 diabetes (T1D) who have, or are at high risk of, diabetic nephropathy. Selected RS will conduct crucial protocol-based research, including performing kidney biopsies. This initiative aims to leverage existing KPMP resources while fostering direct collaboration. The collaborative effort will focus on obtaining and evaluating biopsies to build a comprehensive Kidney Tissue Atlas. This data will facilitate the definition of disease subgroups and the identification of key cells, interstitial components, and pathways. Ultimately, this work is designed to uncover novel therapeutic targets for T1D nephropathy. Current KPMP RS are not eligible.
Opportunity ID: 356552
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-25-022 |
| Funding Opportunity Title: | Precision Medicine for Type 1 Diabetic Nephropathy (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 26, 2024 |
| Last Updated Date: | Sep 26, 2024 |
| Original Closing Date for Applications: | Dec 10, 2024 |
| Current Closing Date for Applications: | Dec 10, 2024 |
| Archive Date: | Jan 15, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $400,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Private institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments For profit organizations other than small businesses Special district governments City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Independent school districts State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Notice of Funding Opportunity (NOFO) requests applications for Recruitment Sites (RS) to enroll adult and/or pediatric patients with Type 1 diabetes (T1D) with, or at high risk of, diabetic nephropathy into a longitudinal cohort study and perform protocol-based research kidney biopsies. These T1D RS will leverage the existing resources of the Kidney Precision Medicine Project (KPMP). T1D RS will collaborate directly with the KPMP to obtain and evaluate kidney biopsies from participants, create a Kidney Tissue Atlas, define disease subgroups, and identify critical cells, interstitial components, pathways, and targets for novel therapies. Current KPMP RS are not eligible to apply. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-25-022.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 356552 Full Announcement-RFA-DK-25-022 -> RFA-DK-25-022-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00287994 | Nov 11, 2024 | Jan 24, 2025 | View |
Package 1
Mandatory forms
356552 RR_SF424_5_0-5.0.pdf
356552 PHS398_CoverPageSupplement_5_0-5.0.pdf
356552 RR_OtherProjectInfo_1_4-1.4.pdf
356552 PerformanceSite_4_0-4.0.pdf
356552 RR_KeyPersonExpanded_4_0-4.0.pdf
356552 PHS398_ResearchPlan_5_0-5.0.pdf
356552 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
356552 RR_Budget_3_0-3.0.pdf
356552 RR_SubawardBudget30_3_0-3.0.pdf
356552 PHS398_ModularBudget_1_2-1.2.pdf
356552 PHS_AssignmentRequestForm_3_0-3.0.pdf
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